1 Derm T Flashcards

1
Q

Chronic lymphedema is risk factor for? (Stewart-Troves Syndrome)

A

angiosarcoma

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2
Q

GVHD can occur with what transplants

A

bone marrow usually but also Liver

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3
Q

Immune related disease with chronic diarrhea and failure to thrive

A

SCID

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4
Q

merocrine vs apocrine vs holocrine

A

merocrine - exocytosis (saliva) apocrine - vesicles (mammary) holocrine - whole cell (sebaceous)

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5
Q

Diff b/w rubella (GM) and rubeola (M)

A

GM spreads faster, does not darken/coalesce, has posterior auricular LAD

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6
Q

German measles vs rubeola, what type of virus

A

togavirus(GM) and paramyxovirus(M)

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7
Q

In which cellular compartment does Vit C aid in collagen synthesis

A

RER

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8
Q

Tennis shaped granule

A

Langerhans cells (Birbeck granules)

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9
Q

dermatitis herpetaformis typically occurs where

A

buttocks and extensor surfaces

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10
Q

Ehlers-Danlos is problem with what?

A

deficiency of pro collagen peptidase deficiency

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11
Q

superficial (strawberry) hemangioms vs cherry hemangioma

A

superficial occurs as kids and regress, cherry will appear in 30s-40s

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12
Q

vitiligo vs albinism

A

vitiligo is destruction of melanocytes; albinism is defective melanocytes

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13
Q

blocks squalene epoxidase

A

terbinafine

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14
Q

blocks B3glucan

A

caspofungin

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15
Q

blocks ergosterol

A

nystatin/amphoB

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16
Q

Unique psoriasis Tx

A

calcipotriene; Vit D analog which activates VitD TF and inhibits keratinocyte production

17
Q

Cidofovir vs acyclovir

A

cidofovir doesn’t require a viral kinase like acyclovir does

18
Q

prostate cancer mutations

A

BRCA 1/2

19
Q

melanoma mutations

A

BRAF

20
Q

target lesions

A

erythema multiform, CD8; associated with HSV