4th Year Extras Flashcards
(59 cards)
What investigations should you perform on someone presenting with chest pain
Bloods - troponin, U&E, FBC
ECG
CXR - look for heart size, signs of heart failure
ABG if hypoxic
Might do amylase, d-dimer, echo, CT chest
What are the main 3 differentials for acute chest pain
Acute Coronary Syndrome -STEMI, NSTEMI etc
PE
Acute Aortic Syndrome - rupture, dissection, penetrating ulcer
List the immediate treatment for an acute coronary syndrome
MONA + T/C
Morphine + anti-emetic Oxygen Nitrates Aspirin \+ Ticegralor or Clopidogrel
How is chronic stable angina managed
With medication - aspirin, statins, b-blocker, GTN
Reciprocal ST depression on an ECG is suggestive of what
That the STEMI is real
e.g. if ST elevation is present it will often have depression in the opposite leads
How can BNP be used to diagnose heart failure
If BNP is low it excludes heart failure
If it comes back high the patient should get an echo to confirm
Which investigations would you do for suspected heart failure
Cardio examination
Basic bloods to check baseline
CXR (not great for diagnosing heart failure itself but can show fluid balance)
ECG
BNP
Can also do MRI and angiogram to determine cause
Cardiopulmonary exercise test - helps assess severity and part of workup for transplant
List some lifestyle changes that can help in the treatment of heart failure
Weight management
Smoking cessation
Diet - salt and fluid restriction
Exercise - cardiac rehabilitation
List some of the medical options for heart failure treatment
Conventional medical therapy - loop diuretics (helps with oedema), B-blocker (reduce mortality), ACEi or ARB
Advanced medical therapy - spironolactone, IV iron (makes them feel better), may also add thiazides, digoxin
New therapy - entresto (combination of ARB and another), SGLT2 (diabetes drug)
List some of the surgical options for heart failure treatment
Pacemakers or implantable defibs
In very advanced cases - intra-aortic balloon pump, LVAD and ECMO (only done pre-transplant in the UK)
Transplants (rare but successful)
What can cause heart failure
LV systolic dysfunction - most common
Valve disease
Arrhythmia
Ventricular dysfunction
The generic term heart failure typically refers to what underlying cause
LV systolic dysfunction
This is the most common and where all the research lies
How does left heart failure present
SOB, PND, orthopnoea, pulmonary oedema (affects the lungs)
How does right heart failure present
SOB (due to pulmonary hypertension not oedema)
Raised JVP
Peripheral oedema
Palpable liver edge (affects venous system
How does acute heart failure present
Basically very acute Breathlessness (severe and acute) Raised JVP Pink frothy sputum Extreme sweating Distress
What can cause acute heart failure
Post MI
Arrhythmia
Blocked artery
Valvular disease (AS, MR etc.)
How do you treat acute heart failure
Sit them up
Oxygen,
Diuretics
Morphine for distress
If BP is good give them nitrates and put on CPAP
If BP is not good then they get inotropes and CPAP
What causes chronic heart failure
Caused by LVSD
This is turn can be caused by hypertension, CAD or IHD and also arrhythmia, myopathy, toxins (alcohol, drugs, radiation, cytotoxic drugs), myocarditis, rheumatic heart disease, sarcoid, malignancy, genetic disorders (DCM)
What are the main purposes of IV fluids (5 R’s)
Resuscitation Replacement Routine Maintenance Redistribution Reassessment
What is the main difference between a crystalloid and colloid fluid
A colloid is much larger molecules so stays intravascular - increases volume and BP
Crystalloid gets into the cell so helps replenish all compartments
Which type of fluid is best for resuscitation
Best approached with a crystalloid rather than colloid
Balanced one like Hartmann’s solution or normal crystalloid like 0.9% saline
What is the issue with giving too much sodium chloride as fluid
Can result in hyperchloremic metabolic acidosis if excessive amounts given
Increased the serum chloride causes a decreases in bicarbonate (both negative charge) in order to maintain electrical balance which in turn causes an acidosis
What is the one situation in which you would use NaCl for large fluid bolus
Rhabdomyolysis (and AKI/CKD) as there is a risk of hyperkalaemia
Normal saline would be preferred as you don’t want to add more K+
Where is most of the fluid distributed to when given IV
Majority is intracellular - this is the body’s biggest compartment