5 Alpha Reductase Inhibitors Flashcards

(46 cards)

1
Q

What is the primary action of 5 Alpha Reductase Inhibitors?

A

They inhibit the conversion of testosterone to dihydrotestosterone (DHT).

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2
Q

Name one common 5 Alpha Reductase Inhibitor.

A

Finasteride.

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3
Q

True or False: 5 Alpha Reductase Inhibitors are used primarily to treat benign prostatic hyperplasia (BPH).

A

True.

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4
Q

What is a major adverse effect of 5 Alpha Reductase Inhibitors?

A

Sexual dysfunction, such as decreased libido.

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5
Q

Fill in the blank: 5 Alpha Reductase Inhibitors can cause __________ in some patients.

A

gynecomastia.

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6
Q

Which of the following is a 5 Alpha Reductase Inhibitor? A) Dexamethasone B) Dutasteride C) Metformin

A

B) Dutasteride.

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7
Q

What is the mechanism of action for 5 Alpha Reductase Inhibitors?

A

They block the enzyme that converts testosterone to DHT.

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8
Q

List one drug interaction with 5 Alpha Reductase Inhibitors.

A

Hormonal therapies.

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9
Q

True or False: 5 Alpha Reductase Inhibitors can be used for male pattern baldness.

A

True.

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10
Q

What should patients be advised to monitor while taking 5 Alpha Reductase Inhibitors?

A

Symptoms of prostate problems and sexual side effects.

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11
Q

Name a condition that 5 Alpha Reductase Inhibitors are NOT typically used to treat.

A

Prostate cancer.

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12
Q

What is the brand name for Finasteride?

A

Proscar.

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13
Q

Fill in the blank: 5 Alpha Reductase Inhibitors may take several __________ to show effects.

A

months.

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14
Q

True or False: 5 Alpha Reductase Inhibitors can affect liver function.

A

False.

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15
Q

What is a common side effect of Dutasteride?

A

Erectile dysfunction.

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16
Q

How do 5 Alpha Reductase Inhibitors affect prostate size?

A

They reduce prostate size over time.

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17
Q

List one contraindication for using 5 Alpha Reductase Inhibitors.

A

Pregnancy.

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18
Q

What is the primary therapeutic use of 5 Alpha Reductase Inhibitors?

A

To treat benign prostatic hyperplasia (BPH).

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19
Q

True or False: 5 Alpha Reductase Inhibitors can cause depression.

20
Q

Which enzyme do 5 Alpha Reductase Inhibitors inhibit?

A

5-alpha-reductase.

21
Q

What should women who are pregnant or may become pregnant avoid?

A

Handling crushed or broken 5 Alpha Reductase Inhibitors.

22
Q

What is the brand name for Dutasteride?

23
Q

True or False: 5 Alpha Reductase Inhibitors are effective immediately.

24
Q

Fill in the blank: 5 Alpha Reductase Inhibitors may lead to __________ changes in sexual function.

25
What should be monitored periodically in patients taking 5 Alpha Reductase Inhibitors?
Prostate-specific antigen (PSA) levels.
26
Name an adverse effect that occurs less frequently but is still serious.
Allergic reactions.
27
True or False: 5 Alpha Reductase Inhibitors can be used in conjunction with alpha-blockers.
True.
28
What is the typical duration of treatment with 5 Alpha Reductase Inhibitors for BPH?
Ongoing, often for many months or years.
29
What is a common reason for discontinuation of 5 Alpha Reductase Inhibitors?
Adverse sexual effects.
30
What role do 5 Alpha Reductase Inhibitors play in hair loss treatment?
They can help with male pattern baldness.
31
List one potential benefit of 5 Alpha Reductase Inhibitors besides reducing BPH symptoms.
Decreased risk of acute urinary retention.
32
True or False: 5 Alpha Reductase Inhibitors can lower testosterone levels.
True.
33
What is the effect of 5 Alpha Reductase Inhibitors on urinary flow?
They improve urinary flow by reducing prostate size.
34
How should 5 Alpha Reductase Inhibitors be taken?
Orally, with or without food.
35
What is a potential risk of long-term use of 5 Alpha Reductase Inhibitors?
Increased risk of high-grade prostate cancer.
36
Fill in the blank: Patients should be informed about the possibility of __________ while taking 5 Alpha Reductase Inhibitors.
sexual side effects.
37
What should patients do if they experience severe adverse effects?
Contact their healthcare provider immediately.
38
True or False: 5 Alpha Reductase Inhibitors can be used in pediatric patients.
False.
39
What is the effect of 5 Alpha Reductase Inhibitors on blood pressure?
They generally do not affect blood pressure.
40
Which condition is a contraindication for the use of Dutasteride?
Hypersensitivity to the drug.
41
Fill in the blank: 5 Alpha Reductase Inhibitors are not recommended for __________.
women.
42
What is a key counseling point regarding fertility for men taking 5 Alpha Reductase Inhibitors?
They may affect sperm count and fertility.
43
What is the recommended starting dose of Finasteride for BPH?
5 mg once daily.
44
True or False: 5 Alpha Reductase Inhibitors can be taken with St. John's Wort.
False.
45
What is the primary reason for the use of 5 Alpha Reductase Inhibitors in hair loss treatment?
To reduce DHT levels.
46
What is an important laboratory test to consider before starting 5 Alpha Reductase Inhibitors?
PSA test.