5. Clinical Pituitary And Adrenal Flashcards Preview

Endocrine M2T2 > 5. Clinical Pituitary And Adrenal > Flashcards

Flashcards in 5. Clinical Pituitary And Adrenal Deck (13)
Loading flashcards...
1
Q

What are the two treatments for prolactinoma

A

Bromocriptine, cabergoline

2
Q

Analog of ACTH, what is it used for

A

DDAP, used to treat central diabetes insipidis

3
Q

Tx for nephrogenic DI

A

Thiazide diuretics, paradoxical effect

4
Q

Supraclavicular fat pad is seen in which disorder?

A

Cushings

5
Q

Order of dosings for test of cushings

A

Overnight, low, high

Suppression tells you it’s pituitary tumor - cushings disease
No suppression with high Dex tells you it’s Cushing’s syndrome (either adrenal tumor or ectopic secretion of ACTH from lungs, pancreas, thymus)

6
Q

Treatment for cushings disease (surgery)

A

Transfrontal resection
Transsphenoidal microsurgery
Bilateral adrenalectomy (what can this result in?)

ANS: Nelson syndrome

7
Q

Three organ sources for ectopic Cushing’s syndrome

A

Lungs pancreas thymus

8
Q

Addison’s disease - what is it

A

Autoimmune. Antibodies against adrenal cortex –> decreased cortisol and aldosterone

9
Q

Addison’s disease features

A

Hypotension, salt wasting, hyperpigmentation, hyponatremia, hyperkalemia, positive anti adrenal antibodies

10
Q

Tx for Addisons

A

DDAP, lV hydrocortisone, florinef (aldosterone)

11
Q

Florinef

A

Aldosterone

12
Q

21 hydroxylase deficiency causes what

A

Increased sex hormones, decreased cortisol and aldosterone

Hirsutism, amenorrhea, salt wasting, hyperpigmentation

13
Q

Difference between pituitary dwarfism and achondroplasia dwarfism (symptom)

A

Achondroplasia: normal trunks, short limbs
Pituitary: proportional everything