5 Infectious Patalim Pearls Flashcards

(33 cards)

1
Q

risk factors for developing cellulitis and erysipelas

A

lymphedema
skin breakdown/site of entry
venous insufficiency
leg edema
obesty
neutropenia
immunocompromise
hypogammaglobulinemia
chronic renal disease
cirrhosis

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2
Q

signs specific for erysipelas

A

butterfly pattern
millian ear sign

peau d’ orange - both ceelulitis and erysipelas

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3
Q

this classically associated with necrotizing soft tissue infection

A

severe pain, anxiety, and diaphoresis

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4
Q

gold standard in diagnosis and treatment of necrotizing soft tissue infection

A

surgery
mortality skyrockets if debridment is delayed >24 hours

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5
Q

single most important feature to make diagnosis early in necrotizing fasciitis

A

pain out of proportion

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6
Q

hard signs of necrotizing fasciitis

A

crepitus, skin necrosis, bullae, hypotension, gas on xray

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7
Q

most reliable sign of necrosis on CT

A

non-enhancing deep tissues

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8
Q

aka Durand-Nicolas-Favre disease

A

LGV

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9
Q

more serious influenza

A

Influenza A

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10
Q

Risk factors for severe influenza

A

children younger than 2y
adults ≥65
comorbid
immunosuppresion
pregnancy
<19y receiving long-term aspirin
morbid obesity

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11
Q

HSV1 resides in

A

trigeminal ganglila

HSV 2 resides in sacral ganglia

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12
Q

hallmark of HSV encephalitis

A

acute onset of fever and neurologic symptoms

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13
Q

independent predictors of a poort outcome for patients with HSV encephalitis

A

GCS ≤6
FOCAL cns LESIONS
INCREASED PATIENT AGE
start of antiviral thearpy >4 days after onset of symptoms

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14
Q

varicella zoster IG is limited to

A

postexposure prophylaxis of nonimmune pregnant women and the severely immunosuppresed

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15
Q

often a clue to an immmuodefficient condition

A

herpes zoster involveing more than three dermatomes

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16
Q

varicella, acyclovir and antivirals decrase the number of lesions and shorten the course if started within

A

24 hours of rash onset

17
Q

herpes zoster, start antiviral wihtin

A

72 hours of rsh onset
start >72 hours if vesicles are still present or patient is immunocompromised

18
Q

HIV: seroconversion and detectable antiresponse at

19
Q

treatment of cyrptococoosis

A

amphotericin B
+ flucytocine

20
Q

most common complaint in tetanus

A

pain and stiffness in the masster muscles (lockjaw)

21
Q

preferred agent for muscle relaxation in tetanus

A

midazolam (water-solubble agent)

lorazepam and diazepam may result in metabolic acidosis secondary to propylene glycol vehicle

22
Q

DOC in uncomplicated malaria

A

artemisinin-containing combination therapies
artemether-lumefrantine
artesunate-amodiaqune

23
Q

antimalarial for sevre (complicated) malaria

A

artesunate
or quinidine gluconate
PLUS
doxycyline
or clindamycin (in children <8y)

24
Q

reversal of hot and colod sensation

A

ciguera toxin (most common in barracuda)

25
tx in ciguera toxin
supportive care high-dose atropine for bradycardia IV manitol for severe neurologic sympotoms
26
toxin in pufferfish
tetrodotoxin
27
tx in pufferfish intoxication
emergent supportive care anticholinesterase such as neostigmein and edrophoneium
28
toxin in tuna
scombroid (histamine
29
most characteristic component of secondary stage of lyme disease
multiple annular/target shaped sin findigns
30
most common neurologic symptom of secndary stage of lyme disease
development of cranial neuritis, most often**unilateral or bilateral facial nerve palsy**
31
classic presentaiton of yellow fever
triad of jaundice black emesis albuminuria death in 7-10 days after onset
32
most common cause of acute themorrhagic fever in temperate climates
neissereia minengitidis
33
preferred HIV postexposure prohylaxis
tenofovir 300 mg + emtriciabine 200 mg OD *PLUS* raltegravir 400,g IBID or dolutegravir 50 mg OD FOR 28 DAYS