5.1 ISBT 004 (Rh Blood Group) Flashcards

(56 cards)

1
Q

Rh Blood Group comes from What chromosome?

A

Chromosome 1

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2
Q

Rh Blood group is ___ most important Blood group

A

2nd

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3
Q

Rh antigen is discovered from?

A

Rhesus Monkey

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4
Q

Rh Antibody was discovered from?

A

Guinea pig and Rabbit

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5
Q

Chromosome # for MNS?

A

4

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6
Q

1st Case related to Rh Blood Group includes Acute Hemolytic Transfusion Reaction from pregnant woman

T or F

A

T

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7
Q

Order of Immunogenicity in Rh group?

A

D > c > E > C >e

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8
Q

Theory of Multiple Allelomorphic genes occuring at a SINGLE Chromosomal Loci

A

Wiener Theory

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9
Q

Theory of pairs of Linked Gene, the antigens of the system were produced by THREE CLOSELY linked sets of Alleles

A

Fisher Race

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10
Q

▪ D gene -> D antigen
▪ C/c gene -> C/c
▪ E/e gene -> E/e

What Theory is this?

A

Fisher Race Theory

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11
Q

Rh genes -> Rho, rh’, rh”

What theory is this?

A

Wiener Theory

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12
Q

What is the Shorthand designation for Rho?

A

Ro

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13
Q

What is the Shorthand designation for rhy?

A

ry

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14
Q

What is the Wiener Agglutination for Rh1

A

Rh1

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15
Q

What is the Fisher Race Antigens for Rhz

A

DCE

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16
Q

What is the Fisher Race Antigens for rhy?

A

CE

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17
Q

What is the Fisher Race Antigens for rh”?

A

cE

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18
Q

What is the Fisher Race Antigens for Rh1?

A

DCe

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19
Q

What is the Fisher Race Antigens for rh?

A

ce

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20
Q

What is the Wiener Blood factors for Rh1

A

Rho rh’ hr”

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21
Q

What is the Wiener Blood factors for Rhz?

A

Rho rh’ rh”

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22
Q

What is the Wiener Blood factors for rh”?

A

hr’ rh”

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23
Q

What is the Wiener Blood factors for rhy?

24
Q

What is the Rosenfield for Rho?

A

1, -2, -3, 4, 5

25
What is the Rosenfield for Rhz?
1, 2, 3, -4, -5
26
What is the Rosenfield for rh"?
-1, -2, 3, 4, -5
27
What is the Rosenfield for rh?
-1, -2, -3, 4, 5
28
What is the Rosenfield for Rh2?
1, -2, 3, 4, -5
29
What is the Rosenfield name if the mother “DCE” and the father “dce”?
1, 2, 3, 4, 5
30
● Mother = DCE/DcE ● Father = dCe/dce Which of the following is not an offspring? a. r/Rz b. R2/r c. Rz/r d. Rz/R2
d
31
Which genotype is heterozygous for "C" a. Ro / R1 b. r / r" c. R1/Rz d. R2 / r"
a
32
If a patient develops anti-"c", what is the genotype?
"C"
33
Which donor unit is selected if the recipient has anti-"c" and Anti-"e"? a. Ro b. R1 c. R2 d. Rz
d
34
Genetics for Rh are inherited as codominant alleles T or F
T
35
Genetic Weak D has a weak D with no antibodies created T or F
T
36
Parenthesis such as (D), (C), (E), indicates strong antigens T or F
F Weark
37
C trans is position effect is where one genotype has capital C while the other is small c T or F
T
38
PArtial D (D mosaic) is where parts of "D" is Missing which creates antibodies T or F
T
39
What is the Test for Weak D or Partial D?
Indirect Antiglobuin test
40
Reporting: A+ Ab screening: Anti D negative a. Partial D b. Genetic weak D
b
41
Reporting: A+ Ab screening: Anti D Positive a. Partial D b. Genetic weak D
a
42
43
An emergency situation where an Indirect antiglobulin test will not be possible at the moment, what blood type should you release after blood typing these 2? a. O+ b. O-
b
44
In Reporting: If the patient has weak D, how should you report for Rh?
Negative
45
In Reporting: If the Donor has weak D, how should you report for Rh?
Positive
46
In HDFN : Mother = D _ Fetus = D _
- +
47
In HDFN: When the mother is in labor, the uterus will be teared causing the baby RBCs (with Rh positive) to enter the blood stream of the mother causing to create anti-D T or F
T
48
Anti-D is IgM T or F
F IgG
49
IgG is warm reacting T or F
T
50
In HDFN: When Anti-D sensitize with Fetal RBC, the RBC will pop T or F
F The Sensitized Fetal RBC will TRY to enter the splenic filter of the fetus but is instead eaten by the macrophage
51
HDFN is intravascular hemolysis T or F
F Extravascular hemolysis
52
How to extract fetal blood for testing of fetal blood?
Cordocentesis
53
HDFN has complement activation T or F
F No complement activation
54
HDFN occurs when mother is _______ and the fetus is_____
D- D+
55
The possibility of the 1st born to have HDN if: - The mother has Anti-D due to transfusion - Abdominal trauma the lead to destruction of placenta T or F
t
56
What are the HDN antibodies?
Anti-Kell (K) Anti-Duffy (a)