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Systemic Pharm Final > Anti-Reumatics > Flashcards

Anti-Reumatics Flashcards

1
Q

What is Hydroxychloroquine [Plaquenil®] used for?

A

It is a Disease Modifying Anti-Rheumatic Drugs (DMARD) used for Rheumatoid Arthritis (RA), systemic lupus erythematosus (SLE), Malaria Prophylaxis (Malaria prophylaxis is started 1-2 wks prior to exposure through 4 wks following exposure)

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2
Q

What is the mechanism of action of Hydroxychloroquine [Plaquenil®]?

A

DMARD which:
Inhibits rheumatoid factor and acute phase reactants.
Interrupts parasitic vesicle functions by increasing pH.
Inhibits phospholipid metabolism by increasing pH.

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3
Q

Side effects of Hydroxychloroquine [Plaquenil®]?

A 
ADVERSE EFFECTS
Common: headache, photosensitivity
SERIOUS ADVERSE EFFECTS
Hypersensitivity: angioedema
Ocular: retinopathy, vision changes
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4
Q

Drug interactions of Hydroxychloroquine [Plaquenil®]?

A

Botox- botox activity is impaired

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5
Q

Contraindications of Hydroxychloroquine [Plaquenil®]?

A

Retinal or visual changes

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Systemic Pharm Final (12 decks)

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