CHAPTER 45- ANTIFUNGAL AND ANTIVIRAL DRUGS

Question 1

Sebastian, a 26 year old male, was diagnosed with HIV 3 months ag and after a large number of tests, the decision was made to commence treatment with a combination regimen of Tenofovir (NRTI), Efavirenz (NNRTI) and Antananarivo (PI) with low dose riot avid (PI).

Answer 1

Sebastian, a 26 year old male, was diagnosed with HIV 3 months ag and after a large number of tests, the decision was made to commence treatment with a combination regimen of Tenofovir (NRTI), Efavirenz (NNRTI) and Antananarivo (PI) with low dose riot avid (PI).

Question 2

1. Discuss the rationale for treatment with 2 NRTIs, 1 NNRTI and PI.

Answer 2

.NRTI’s and NNRTI’s work together to stop the HIV replicating so the amount of virus in the body to go down. PI inhibit the lopinavir.

Question 3

2. Explain why low dose ritonavir has been included in this regimen

Answer 3

.• It effectively increases the plasma concentration of the PI.