5.2 Phagocytosis Flashcards
(4 cards)
What is phagocytosis
The cellular process of engulfing solid particles by the cell membrane to form an internal phagosome by phagocytes
What is the process of phagocytosis
~ Phagocyte e.g. macrophage recognises foreign antigens on the pathogen and binds to the antigen
~ phagocytes engulf the pathogen by surrounding it with its cell surface membrane / cytoplasm to form a vesicle called the phagosome
~lysosome fuses with the phagosome and release lysozymes into the phagosome which destroy the ingested bacteria ( pathogen) by hydrolysis of their cell walls
~ the phagocytes absorbs the soluble products of the bacterium hydrolysis
~ Phagocyte becomes antigen presenting and stimulates specific immune response
What type of lymphocytes are involved in specific immune response
T-LYMPHOCYTES: cell- mediated immunity ( involves body cells ), mature in the thymus gland
B-LYMPHOCYTES: humoral immunity (involves body fluids ) , mature in bone barrow
Has does our body recognise our own cells
~each type of our body cells has specific molecules on its surface that identify it, these molecules have specific proteins with a highly specific 3D- tertiary structure which distinguishes one cell from another.
~these molecules also help the immune system to identify pathogens, toxins, abnormal body cells etc