Dr. Pelletier Flashcards

1
Q

What does not change in the Hardy Weinberg Equilibrium?

A

Relative frequencies of genotypes

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2
Q

Hardy Weinberg Equation:

A

Genotypes = p^2+ 2pq+ q^2

p+q=1 (allele frequencies)

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3
Q

Five conditions for hardy weinberg:

A
  1. ) Large population
  2. ) Random mating
  3. ) No natural selection
  4. ) No mutation
  5. ) No gene flow in or out of population
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4
Q

What is positive assortment?

A

Mate selection based on similar ethnic backgrounds, physical traits, intelligence, religious background

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5
Q

What is consanguinity?

A

No MRCA more closely related than great-great grandparent

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6
Q

Issue with consanguinity?

A

More homozygotes for particular genes

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7
Q

What occurs with mutation?

A

Rate of introduction and rate of elimination cancel via natural selection having no impact on HW equation

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8
Q

Fitness:

A

Fitness= 1 - selection coefficient

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9
Q

What is the Founder Effect responsible for?

A

Population specific differences in the frequency of specific disease

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