Lecture 2 Flashcards

1
Q

What type of hormone is GnRH?

A

Neuropeptide

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2
Q

What is the origin of GnRH?

A

Hypothalamus

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3
Q

What is the target of GnRH?

A

Anterior pituitary

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4
Q

What is the function of GnRH?

A

To stimulate production and release of FSH and LH

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5
Q

What hormone promotes GnRH release?

A

Estrogen

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6
Q

What type of hormone is FSH?

A

Glycoprotein

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7
Q

What is the origin of FSH?

A

Anterior pituitary

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8
Q

What is the target of FSH?

A

Ovary (granulosa cells)

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9
Q

What is the function of FSH?

A

Follicular development

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10
Q

What type of hormone is LH?

A

Glycoprotein

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11
Q

What is the origin of LH?

A

Anterior pituitary

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12
Q

What is the target of LH?

A

Theca and granulosa cells

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13
Q

What is the function of LH?

A

Follicular maturation

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14
Q

What do theca cells produce and from what is this produced?

A

Theca cells produce androgens from cholesterol

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15
Q

What do granulosa cells produce and from what is this produced?

A

Granulosa cells produce estrogens from androgens

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16
Q

Which subunit is the same between both FSH and LH?

A

Alpha subunit

17
Q

What is the origin of estrogen?

A

Follicles

18
Q

What is the target of estrogen?

A

Pituitary and hypothalamus

19
Q

What is the function of estrogen?

A

Promotes GnRH release from the hypothalamus

20
Q

What type of hormone is inhibin?

A

Glycoprotein

21
Q

What is the origin of inhibin?

A

Granulosa cells in the dominant ovarian follicle

22
Q

What is the target of inhibin?

A

Anterior pituitary

23
Q

What is the function of inhibin?

A

Suppresses production and secretion of FSH

24
Q

What type of hormone is progesterone?

A

Steroid hormone

25
Q

What type of hormone is estrogen?

A

Steroid hormone

26
Q

What is the target of progesterone?

A

Hypothalamus

27
Q

What is the origin of progesterone?

A

CL or placenta

28
Q

What is the function of progesterone?

A
  1. Maintenance of pregnancy

2. Suppress secretion of GnRH from hypothalamus

29
Q

What type of substance is PGF2-alpha (prostaglandin)?

A

Fatty acid

30
Q

What is the origin of PGF2-alpha?

A

Endometrium

31
Q

What is the target of PGF2-alpha?

A

CL

32
Q

What is the function of PGF2-alpha?

A

Lysis of the CL