Ch 3 Flashcards
Structural changes in the heart
Thickening of the blood vessels and left ventricle.
Aorta stiffens
Increase size of left atrial chamber
Inotropic function
Contractility of heart. The strength of heartbeat
Chronotropic function
Heart rate. Speed at which the heart beats
Lusitropic function
The relaxation of the heart
Frank-Starling mechanism
More heart volume means more contractility = stroke volume
What changes to the heart rhythm with age? Rest vs exercise
More input during rest than when young.
Less raise in input during exercise than when young.
Maximal HR drop due to catacholmines, why?
Catacholmine exposure: overstimulation causing desensitvity
Why does O2 diffusion go down in adults?
Thickness of wall means less diffusion to go through
What types of muscles are more prevalent in aging adults?
Type I
TPR up or down with age? Why?
Up 1% / yr
More rigid of vessels. Less biochemical mechanisms for vasodilation (endothelial NO)
a-receptors deal with?
b-receptors deal with?
Why is there a tendency for vasoconstriction with age?
a-receptor: vasoconstriction
b-receptor: vasodilation
a-receptors responsiveness improves with exercise, b-receptors responsiveness decreases with age.
What are some issues with baroreceptor responses and age?
Systemic BP drops causing lightheadedness.
= Hypotension
Hypertension is more prevalent in what sex?
What phase is most problematic?
Females. Systolic phase
How can one, in theory, reduce a high drop in VO2 Max?
By being more active at a younger age, a higher point to which VO2 Max begins to drop means a higher VO2 Max later in life.
What is the only element of human frailty that is controllable?
Disuse: not being sedentary