Pharma 13.1 Acid Secretion Drugs Flashcards
1
Q
What are the 3 molecules that can act on parietal cells to upregulate acid secretion? What cells do they act on?
A
gastrin - CCK-B receptor
Histamine - H2 receptor
ACh - M3 receptor
2
Q
Name a H2 antagonist
A
Ramitidine. Cimetidine
3
Q
Name H2 antagonist ADRs
A
diarrhoea, rashes, headache
4
Q
Name 3 example PPIs
A
Omeprazole, lansoprozole, esomeprazole
5
Q
Give ADRs of PPIs
A
headache, diarhoea, rashes
6
Q
How do you treat H pylori?
A
1 week clarithromycin, amoxicilline, omeprazole
