Ch 22 Flashcards

1
Q

Basophils

A

Circulate blood

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2
Q

Two pro-inflammatory chemical-secreting cells

A

Basophils

Mast cells

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3
Q

Bacteria

A

Single called

1-2 micrometers

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4
Q

Inflammation

A

Release of chemicals

Vasodilation

Recruitment of immune cells

Delivery of plasma proteins

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5
Q

Vaccines produce

A

Artificially acquired active immunity

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6
Q

Antibody titer

A

Antibody concentration in the blood

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7
Q

Cytotoxic T cell

A

Destroys infected cells with apoptosis

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8
Q

Plasma cell

A

Produce antibodies

5 day lifespan

Spent in lymph nodes

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9
Q

Helper T cell

A

Releases interleukins and cytokines to stimulate other cells

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10
Q

Humoral immunity

A

Antibody-mediated immunity

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11
Q

Phagocytes

A

Macrophages

Neutrophils

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12
Q

Active immunity

A

Development of memory cells

Direct contact with antigen

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13
Q

Immune surveillance

A

Natural killer cells are able to detect unhealthy cells

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14
Q

Opsonization

A

Marking a target for phagocytosis

Facilitated by interaction of Fc region of antibody with a phagocyte

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15
Q

Antigenic determinant

A

Binding site

Part of immune system recognizes and binds to foreign molecule

Aka epitope

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16
Q

Prions

A

Small fragments of infectious proteins that cause disease in nervous tissue

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17
Q

Immunocompetent

A

Lymphocytes able to bind and respond to an antigen

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18
Q

Eosinophils

A

Most effective to attack multicellular parasites such as tapeworms

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19
Q

Adaptive immunity

A

Delayed response

Acquired

20
Q

Complement refers to a group of

&facilitate inflammation by

A

Plasma proteins

Activating basophils and mast cells and by attracting macrophages and neutrophils

21
Q

Pyrogens

A

Act on hypothalamus

Release PGE2

22
Q

Viral capsids made from

A

Capsomeres

23
Q

Lysis

A

Release of non enveloped virus

24
Q

Oncovirus

A

Mammalian viruses capable of starting tumors

25
Q

Latent virus

A

Alternating periods of activity with symptoms and no symptoms with inactivity

26
Q

Viral spikes

A

Attach to viral capsid and envelope

27
Q

Uncoating

A

Dissolving envelope

Capsid releases nucleic acid

28
Q

Lysogeny

A

Viral genome inserting into bacterial host chromosome

29
Q

Cytokines

A

Proteins

Serve as chemical messengers

30
Q

Virus

A

Composed of nucleic acid within a protein capsid

31
Q

Cytotoxic T-lymphocytes destroy infected cells by releasing

A

Perforin and granzymes

32
Q

Antibodies

A

Effectors of humoral immunity

33
Q

Secondary response of immune system involves

A

More cells than the antigen challenge

Due to proliferation of memory cells

34
Q

IgM

A

Pentamer

Agglutination of mismatched blood

35
Q

IgA

A

Found in tears, saliva, mucus

36
Q

IgG

A

Most prevalent antibody in blood and lymph

37
Q

As T-lymphocytes leave the thymus they are

A

Naive and immunocompetent

38
Q

Bovine spongiform encephalopathy

A

Consuming meat that has been infected with a prion can lead to this

39
Q

Interferon

A

Released by virus infected cell to prevent the spread of infection

40
Q

Mast cells

A

Resemble basophils

Found in CT and close to small blood vessels

41
Q

Kinins

A

Proteins

Produced by a variety of cells

Increase capillary permeability

Increase CAM production in endothelium

Stimulate pain receptors

42
Q

Antigen presentation

A

Antigen displayed on surface of cell so T-lymphocyte can be exposed to it

43
Q

Membrane attack complex

A

Forms a channel in the target cell membrane that causes cytolysis

44
Q

Neutralization

A

Antibody covers a specific region of virus to bind to cell receptor

45
Q

Fever

A

Inhibits reproduction of bacteria

Increases CAMs in the endothelium and capillaries of lymph nodes