Microtubule Accessory Proteins

Question 1

Stathmin

Answer 1

Binds tubulin subunits stops them form assembling

Question 2

gamma (y)-TuRC

Answer 2

Is concentrated in the centrosome.

Question 3

Centrisome

Answer 3

Has the centrioles within it
pericentriolar material outside
Ringed with gamma - TuRC

Question 4

+TIPs

Answer 4

Remains associated with the growing plus end and can link them to others structures such as membranes. This allows the microtubule to still grow and push off or push a structure

Question 5

XMAP215

Answer 5

XMAP215 accelerates growth of + end of the microtubule by stabilizing it through binding

Question 6

MAPs

Answer 6

Stabilizes the whole microtubule by binding along its sides.

Question 7

Katanin

Answer 7

Severs microtubules like a katana!

Question 8

Plectin

Answer 8

Links intermediate filaments to microtubules

Question 9

Kinesin-13

Answer 9

causes catastrophe for microtubules

Question 10

Tau

Answer 10

links with microtubules in a close proximity. It is only in the axon

Question 11

MAP2

Answer 11

Binds in a spread out fashion and exists in the soma and dendrites

Question 12

EB1 protein

Answer 12

Is a capping protein that binds with Kar9 protein.