Genetics of Sex Determination Flashcards
What are the gonadal characteristics of someone that is 46 XY, but has a mutation in SRY?
Undifferentiated gonad is all that’s left
•NO sertoli OR leydig cells
• NOT an ovary because more factors are needed to have a full blown ovary
What are the two purposes of meiosis?
- Reduce Ploidy
2. Shuffle Genetic material to increase genetic variation
What are the main actions of DHT on the male genitals?
- Fusion of the genital folds to form the scrotum
2. Elargement of genital tubercle to form the penis
What primitive tissues become the labia and lower vagina in females?
Genital Folds => Labia
Perineal Body (invagination) => Vagina
Which sex is most susceptible to mitotic errors?
Males - these typically occur as males age
T or F: at puberty testosterone is the hormone responsible for sperm maturation
True
What is the reductive phase in speratogenesis and oogenesis?
Meiosis 1
What happens in the sperm capacitation reaction?
Sperm Develops a Head and a tale and sheds it mitochondria to move more efficiently
When does Meiosis I START in a female?
Month 3 of PREnatal development (as a fetus)
What is the biggest difference in TIMING of male and female gametogenesis?
Female gametogenesis is largely completed by birth
What are the stages in prophase I?
Leptotene Zygotene Pacytene Dipolotene Diakenesis
Leptotene
Chromosomes are replicated and just lie on top of each other
Zygotene
Homologous pairs move together and SYNAPSE
Pacytene
1st time you see a BIVALENT CHROMOSOME (tetrad)
Diplotene
Crossing over occurs
