Week six- Cellular oxidation Flashcards

1
Q

What is the propose of cellular oxidation?

A

Provides energy to re-synthesise ATP in the presence of O2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How does cellular oxidation provide energy to re-synthesis ATP?

A

Breakdown of CHO, lipid and protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is oxidation?

A

Giving up electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is reduction

A

Gaining electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the co-enzymes involved?

A

NAD and FAD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Energy transfer during the ETC.

In three of the four cytochromes the free energy release of electron transfer is associated with what?

A

‘Proton pumping’ from the matrix to the intermembranous space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Energy transfer during the ETC.

Where do the protons accumulate?

A

Outside the mitochondrial matrix (cytosolic side)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Energy transfer during the ETC.

What happens when the protons flow back down their concentration gradient into the matrix?

A

Sufficient energy is release to phosphorylate ADP—>ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How much ATP does each pair of protons produce from NAD?

A

3 ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How much ATP does each pair of protons produce from FAD?

A

2 ATP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Why is food broken down?

A

For it’s electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What allows ATP resynthesis?

A

electron transfer and proton pumping

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What must be present to accept electron at the end of the ETC?

A

Oxygen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Why is cellular oxidation important?

A
  • A cells primary means of extracting and trapping chemical energy.
  • 90% of ATP synthesis takes place via oxidative reaction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where does cellular oxidation occur?

A

In the inner lining of mitochondria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Does cellular oxidation involve the transfer of electrons to oxygen?

A

Yes

17
Q

During ETC what drive the protons out of the matrix when they return ATP is produced?

A

Energy

18
Q

What happens if O2 is limited?

A
  • The electron flow will back up
  • NADH+H+/HADH2 will accumulate
  • Flow through krebs cycle is reduced.
19
Q

How do we continue to exercise when oxygen is limited?

A

Increase anaerobic energy turnover

20
Q

What does the body do when we increase anaerobic energy turnover?

A

Hydrogen removed from NADH+H+ by pyruvate, resulting in lactate formation, meaning pH will drop.

21
Q

What is low pH associated with?

A

Reduced muscle function