Viral drugs and mechanism of action Flashcards

1
Q

acyclovir

A

blocks viral DNA polymerase

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2
Q

darunavir

A

HIV protease inhibitor

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3
Q

efavirenz

A

non-nucleotide reverse transcriptase inhibitor

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4
Q

enfuvirtide

A

viral entry inhibitor

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5
Q

foscarnet

A

blocks viral DNA synthesis

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6
Q

interferon

A

regulates the Jak-STAT pathway and gene expression

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7
Q

ledipasvir

A

inhibits Hepatitis C NS5A, req. for RNA synthesis

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8
Q

maraviroc

A

binds CCR5 and blocks HIV interaction with T cell and monocyte

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9
Q

oseltamivir

A

Neurominidase inhibitor

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10
Q

paritaprevir

A

inhibits Hepatitis C protease

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11
Q

raltegravir

A

inhibits HIV integrase

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12
Q

ritonavir

A

HIV protease inhibitor, also, strong inhibitor of Cyp3A4

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13
Q

sofosbuvir

A

inhibits Hepatitis C RNA polymerase (NS5B)

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14
Q

tenofovir

A

nucleoside/nucleotide reverse transcriptase inhibitors

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