Inflammatory Myopathies

Question 1

biopsy poly/dermatomyositis vs inclusion body myositis

Answer 1

poly/dermatomyositis = necrosis of type 1 and 2 fibers.

inclusion body myositis = eosinophilic inclusion bodies

Question 2

muscle weakness distribution of poly/dermatomyositis vs inclusion body myositis

Answer 2

poly/dermatomyositis weakness is proximal and symmetric.

inclusion body myositis weakness is proximal and distal and asymmetric.

Question 3

2 types of inflammatory myopathies

Answer 3

polymyositis/dermatomyositis and inclusion body myositis

Question 4

NCS of poly/dermatomyositis vs inclusion body myositis

Answer 4

poly/dermatomyositis = normal SNAP and CMAP

inclusion body myositis = abnormal SNAP and CMAP

Question 5

gottron’s sign

Answer 5

red purple patches over knucles, knees and elbows seen in dermatomyositis

Question 6

treatment of poly/dermatomyositis vs inclusion body myositis

Answer 6

poly/dermatomyositis = IVIg, steroids, plasmapheresis

inclusion body myositis = no treatment except for rehab

Question 7

etiology of inflammatory myopathies

Answer 7

poly/dermatomyositis is autoimmune/infection/cancer and inclusion body myositis is unknown

Question 8

which inflammatory myopathy is associated with polyneuropathy

Answer 8

inclusion body myositis