Lymph nodes

Question 1

anus below dentate

Answer 1

superficial inguinal LN

Question 2

glans penis, penile urethra and posterior calf

Answer 2

deep inguinal nodes

Question 3

superior portion of the bladder

Answer 3

external iliac LN

Question 4

inferior portion of the bladder

Answer 4

internal iliac LN

Question 5

prostate

Answer 5

internal iliac LN

Question 6

testes

Answer 6

para-aortic LN

Question 7

upper third of rectum

Answer 7

inferior mesenteric LN

Also drains sigmoid colon

Question 8

Metastatic prostate cancer spread to vertebra how?

Answer 8

Prostatic venous plexus –> vertebral venous plexus

Question 9

Metastatic breast and lung cancer spread to thoracic spine how?

Answer 9

Azygos vein –> vertebral venous plexus

Question 10

Where does isotype switching occur?

Answer 10

germinal center

Question 11

Where does negative selection (deletion of T cell clones that strongly bind self-MHC ag) occur?

Answer 11

Fetal thymus

Question 12

Where does VDJ recombination of immunoglobulin heavy chains occur?

Answer 12

Bone marrow (during B- cell maturation)

Question 13

Where does affinity maturation occur?

Answer 13

germinal centers

Question 14

Where do B-cell precursors proliferate and mature?

Answer 14

Bone marrow

Question 15

Metastasis of SCC of cervix drain where first?

Answer 15

Internal iliac

Question 16

B cells are located in what part of the LN?

Answer 16

Cortex

Question 17

T cells are located in what part of the LN?

Answer 17

Paracortex (hypertrophy in mono)

Question 18

T cells are located where in the spleen?

Answer 18

White pulp (PALS)

Question 19

Lesions of medial foot

Answer 19

Superficial inguinal LN (medial track)

Question 20

Lesions of lateral foot

Answer 20

Popliteal and inguinal LN (lateral track)

Question 21

Scrotum, perineum, butt, skin of penis, ant abdominal wall (inf to umbilicus)

Answer 21

Superficial inguinal LN

Question 22

upper 1/3 of esophagus

Answer 22

cervical nodes

Question 23

middle 1/3 of esophagus

Answer 23

mediastinal or tracheobronchial nodes

eg scc

Question 24

lower 1/3 of esophagus

Answer 24

celiac and gastric nodes (eg adenocarcinoma)

Question 25

left suprclavicular node (virchow node)

Answer 25

gastric carcinoma

Question 26

lower 1/3 of vagina

Answer 26

inguinal nodes

Question 27

upper 2/3 of vagina

Answer 27

regional iliac nodes

Question 28

Middle third of rectum

Answer 28

Internal iliac LN

Note: upper third goes to inf mesenteric; below dentate goes to superficial inguinal