Synapses Flashcards
Describe the vesicular hypothesis
The idea that neurotransmitter is packaged into synaptic vesicles and released in quanta (unit events) of roughly the same size
Synaptic integration
Decision made about whether or not to fire an ap based on product of interactions of collective inputs
Where are decisions made in neurons and why?
Axon hillock in the spike initiation zone (SIZ)
Synaptic integration happens here because there is a very high concentration of voltage-gated ion channels
Space constant
Lamda
Aka length constant
Distance along a neuron that a electrical potential can travel before it dissipates
Time constant
Time it takes for potential to decay at one point along the membrane
Membrane capacitance x membrane resistance
Higher capacitance= longer time constant
High Rm= longer time constant