57 Flashcards

(60 cards)

1
Q

Why is the cerebellum called a ‘silent area’?

A

Because electrical stimulation of the cerebellum doesn’t cause movement or sensation, but damage causes uncoordinated, strange movements.

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2
Q

What is the cerebellum’s role in fast, complex movements?

A

It organizes, controls, and corrects body movements during activities like running, playing the piano, typing, or speaking.

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3
Q

How does the cerebellum help coordinate movement?

A

That sentence means:

👉 The cerebellum acts like a comparator or quality-control center for movement.

Here’s how:
🧠 Motor areas in the brain (like the motor cortex) send a signal to muscles to make a movement — this is the intended movement.
📡 At the same time, that signal is also sent to the cerebellum (called an efference copy).
🦵 The body starts moving, and sensory receptors (like proprioceptors in muscles and joints) send back information to the brain about what actually happened — this is the actual movement.
🧠 The cerebellum compares:
What was supposed to happen (intended movement)
What really happened (actual movement)
🛠️ If there’s a difference (e.g., you’re reaching too far or too short), the cerebellum sends a correction signal to help fix the movement in real-time.

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4
Q

What are the two types of information the cerebellum receives?

A

1) From the motor cortex: intended movements. 2) From the body: actual position, movement, and forces.

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5
Q

What happens when there’s a difference between intended and actual movement?

A

The cerebellum sends fast, automatic correction signals to the motor system to fix the movement immediately.

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6
Q

How does the cerebellum help with smooth movements?

A

It plans the next movement while the current one is ongoing and learns from mistakes to improve future movements.

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7
Q

What are the three lobes of the cerebellum?

A

1) Anterior lobe
2) Posterior lobe
3) Flocculonodular lobe

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8
Q

What is special about the flocculonodular lobe?

A

It is the oldest part of the cerebellum and works with the vestibular system to control balance and body position.

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9
Q

What are the functional zones along the length of the cerebellum?

A

1) Vermis – controls trunk, neck, shoulder, and hip muscles.
2) Intermediate zone – controls limb muscles.
3) Lateral zone – plans/times complex movements.

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10
Q

What does the vermis control?

A

Muscles of the trunk, neck, shoulders, and hips.

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11
Q

What does the intermediate zone control?

A

Limb muscles, especially hands, fingers, feet, and toes.

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12
Q

What does the lateral zone do?

A

Works with the cerebral cortex to plan and time complex, fast movements.

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13
Q

What body areas do the vermis and intermediate zones map to?

A

Vermis maps the central body; intermediate zones map limbs and face.

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14
Q

Where do vermis and intermediate zones send and receive signals?

A

From and to matching body parts, brainstem, motor cortex, red nucleus, and reticular formation.

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15
Q

What inputs do lateral cerebellar areas receive?

A

From frontal and parietal lobes for planning and sensory processing.

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16
Q

What is the cerebellar cortex?

A

A thin, folded sheet about 17 cm wide and 120 cm long. Each fold is called a folium.

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17
Q

What lies under the cerebellar cortex?

A

The deep cerebellar nuclei, which process most output.

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18
Q

.

A

.

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19
Q

Describe the corticopontocerebellar pathway.

A

From motor, premotor, and sensory cortex → pontine nuclei → lateral cerebellum on opposite side.

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20
Q

What is the olivocerebellar tract?

A

From inferior olive to all parts of cerebellum, activated by motor cortex, basal ganglia, spinal cord, and reticular formation.

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21
Q

Vestibulocerebellum – location

A

Includes the flocculonodular lobes and nearby parts of the vermis; these are small areas under the back of the cerebellum.

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22
Q

Vestibulocerebellum – function

A

Controls movements that maintain balance. Works closely with the vestibular system of the inner ear.

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23
Q

Spinocerebellum – location

A

Includes most of the vermis (front and back) and adjacent intermediate zones.

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24
Q

Spinocerebellum – function

A

Coordinates limb movements, especially of the hands and fingers.

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25
Cerebrocerebellum – location
Made up of the lateral cerebellar hemispheres, next to intermediate zones.
26
Cerebrocerebellum – inputs and outputs
Receives from motor, premotor, and somatosensory cortex; sends feedback signals back to the brain.
27
Cerebrocerebellum – main role
Helps plan sequential voluntary movements before they occur (motor imagery).
28
Vestibulocerebellum – evolution and damage effect
Evolved with vestibular system. Damage leads to major balance problems, especially during quick directional changes.
29
Why can’t balance rely only on feedback?
Sensory signal delay (15–20 ms) is too long. Feet can move 10 inches before the signal reaches the brain.
30
How does cerebellum compensate for delay in balance?
Uses rate/direction info to predict next position and prepare movements in advance.
31
Spinocerebellum – input types
1) From motor cortex/red nucleus = planned movement; 2) From proprioceptors = actual movement.
32
Spinocerebellum – comparison & correction
Compares plan vs actual movement. Sends corrections via interposed nucleus to motor cortex and red nucleus.
33
Rubrospinal tract – function
Works with corticospinal tract to control distal motor neurons, especially for hand and finger coordination.
34
Feedback tracts to cerebellum
Dorsal spinocerebellar (sensory input), Ventral spinocerebellar (efference copy of motor commands).
35
Inferior olivary complex – role
Receives mismatch signal and helps correct movement via olivary–Purkinje learning system.
36
Cerebellar damping – importance
Prevents overshoot in momentum-based systems. Stops movement precisely at the target.
37
What is intention tremor?
A back-and-forth tremor from cerebellar damage when correcting overshoot errors.
38
Cerebellar control of ballistic movements
Plans and executes fast actions (typing, saccades) that finish before feedback can be used.
39
Damage effect on ballistic movements
Slower start, weak force, overshooting – due to missing start/stop help from cerebellum.
40
Timing circuit in ballistic movement
Two-phase signal (excitatory then inhibitory) for precise fast actions.
41
Cerebrocerebellum – planning function
Plans and times complex hand, finger, and speech sequences using signals from premotor and somatosensory cortices.
42
Cerebrocerebellum – damage effect
Poor coordination in complex tasks even if primary motor cortex is fine.
43
Dentate nucleus – prediction role
Fires in advance of next movement, helping smooth transitions between fast actions.
44
Cerebellar timing – importance
Controls exact movement timing. Damage leads to delays and poor sequencing.
45
Non-motor timing role of cerebellum
Helps predict fast-changing sensory patterns (e.g. sounds, visuals) using internal clock.
46
Example of timing error in damage
Monkey without lateral cerebellum crashes into walls – can’t predict arrival time.
47
Cerebellar cortex vs nuclei – damage
Cortical loss may show little effect; deep nuclei damage causes serious, lasting issues.
48
Dysmetria – definition
Overshooting or undershooting a target due to cerebellar prediction loss.
49
Ataxia – definition
Uncoordinated movement caused by dysmetria.
50
Cause of dysmetria/ataxia besides cerebellum
Damage to spinocerebellar tracts, which carry feedback needed for timing.
51
What is past pointing?
Movement goes past the target due to missing cerebellar stop signal.
52
Dysdiadochokinesia – definition
Inability to perform rapid alternating movements, like flipping hand up and down.
53
Dysarthria – definition
Disordered speech due to uncoordinated mouth/larynx/respiratory muscles.
54
Cerebellar nystagmus – cause and symptom
Caused by flocculonodular damage; eyes tremble when trying to fixate laterally.
55
Hypotonia – definition and cause
Decreased muscle tone on one side due to deep nuclei (dentate/interposed) loss.
56
Basal ganglia – function overview
Extra motor system. Works with cortex and corticospinal system to refine movements.
57
Basal ganglia – major components
Caudate, Putamen, Globus pallidus, Subthalamic nucleus, Substantia nigra.
58
Basal ganglia – location
Deep in cerebral hemispheres around the thalamus; internal capsule separates caudate and putamen.
59
Putamen circuit – function
Controls learned motor patterns (e.g., writing, speaking, cutting, eye motion).
60
Putamen circuit – pathway
Cortex → Putamen → Globus pallidus → VA/VL thalamus → Motor cortex → (extra loops through GPe, STN, SN).