IBS

Question 1

What age range does IBS affect the most? gender?

Answer 1

young pts: 20-40 Women

Question 2

What are psychological risk factors associated with IBS? What is a well recognized risk factor?

Answer 2

anxiety
chronic pain syndromes
personality disorders
sexual abuse

Bacterial or viral gastroenteritis = postinfectious IBS

Question 3

what is the definition of constipation?

Answer 3

> 3 days of hard stools that are painful/difficult to pass

Question 4

What is the criteria called that is used for IBS? what are the criteria?

Answer 4

Rome IV criteria:

1. Recurrent abdominal pain at least 1 day/week in the last three months a/w 2 or more of the following:
   a) related to defecation
   b) a/w a change in stool frequency
   c) a/w a change in stool form

25% of bowel movements have to be constipation of diarrhea

Question 5

Small intestinal bacterial overgrowth (SIBO) may cause what type of IBS? what is the treatment?

Answer 5

IBS-D

xifaxan

Question 6

What HLA genotype is associated with Celiac disease like symptoms?

Answer 6

HLA-DQ2

HLA-DQ8