Reading 1/30 Cementum-Alveolar Bone Flashcards

1
Q

What makes up the periodontium?

A

Gingiva, root cementum, alveolar bone, PDL

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2
Q

2 parts to the gingiva:

A

gingival epi, gingival CT

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3
Q

This house the root:

A

alveolar bone

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4
Q

This cover the root:

A

cementum

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5
Q

Major component of root formation:

A

dentin

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6
Q

This allows for the laying down of dentin:

A

differentiation of odontoblasts

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7
Q

Cementum is the __ and __ of cementoblasts

A

origin and differentiation

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8
Q

2 parts of alveolar bone:

A

alveolar bone proper, supporting bone

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9
Q

What forms the Hertwig’s root sheath (HRS)?

A

IEE and OEE, after crown completion

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10
Q

Movement of crown w inc root length:

A

away from crypts

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11
Q

What is HRS?

A

bilayer

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12
Q

TF? Root lengthens at same rate tooth moves occlusally.

A

T

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13
Q

What surround the OEE?

A

ental folicle

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14
Q

These cells differentiate into odontoblast:

A

dental papilla cells in contact with IEE

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15
Q

Root development depends on what type of interaction?

A

epi-mesenchymal interaction

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16
Q

This leads to the production of HRS cells:

A

proliferation and downgrowth of IEE and OEE cells

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17
Q

These cell lay adjacent to the HRS cells during the downgrowth:

A

dental papilla cells

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18
Q

What lay above the DP cells during the downgrowth of the HRS cells?

A

differentiating odontolbasts

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19
Q

IEE cells of the HRS do this after crown formation is completed:

A

induce differentiation of Dp cells into preodontoblasts and odontoblasts, odontoblasts from root dentin bw crown dentin and HRS

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20
Q

FLow chart of differentiation starting at proliferation zone:

A

IEE(HRS), Dp cells, preodontoblasts, odontoblasts, root dentin, dentin

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21
Q

What happens as dentin formation continues:

A

root elongates, HRS becomes separated from crwn located at the apical end

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22
Q

At which end is the HRS located during root formation?

A

apical end

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23
Q

What happens after completion of root formation

A

HRS disappears, remnants form epi rest in PDL

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24
Q

Where do epi rests remain?

A

in the PDL

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25
Q

Cementum is what type of tissue:

A

thin, mineralized

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26
Q

Cementum covers:

A

root dentin surface

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27
Q

is cementum vascular or avascular?

A

avascular

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28
Q

Function of cementum:

A

anchors PDL collagen fibers to root

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29
Q

3 types of cementum:

A

intermediate, Acellular, cellular

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30
Q

Location of acellular cementum:

A

cervical 2/3

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31
Q

Location of cellular cementum:

A

apice 1/3

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32
Q

primary cementum:

A

acellular

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33
Q

2’ cementum:

A

cellular

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34
Q

TF? Cementum contains more mineral that bone and dentin.

A

F. less than

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35
Q

Cementum is histologically similar to:

A

bone

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36
Q

What makes cementum similar to bone?

A

lacunae, incremental deposition line

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37
Q

Difference bw cementum and bone:

A

no Harvesian canals, no BV’s or nerves

38
Q

Organic composition of cementum, bone and dentin respectively:

A

50-55%,. 30-35%, 30%

39
Q

Mineral composition of cementum, bone and dentin respectively:

A

45-50%, 60-65, 65.5%

40
Q

Cementum is mainly composed of what type of collagen?

A

Type I (90%)

41
Q

These are responsible for mineralization:

A

non-collagenous proteins

42
Q

3 non-collagenous proteins involved in cementum mineralization

A

bone sialoprotein, osteocalcin, osteopontin

43
Q

3 major organic components of cementum:

A

Type I collage, non-collagenous proteins, GAGs

44
Q

2 types of GAGs found in cementum:

A

chondroitin sulfate, heparan sulfate

45
Q

This make up the 50% inorganic part of cementum:

A

ca and phosphate: hydroxyapetite crystals

46
Q

Arrange bone, enamel, cementum, and dentin from hardest to softest tisse

A

enamel (90%) > dentin (67%) > bone (50-60%) > cementum (45-50%)

47
Q

Most common relation of cementum to enamel:

A

overlapping (60%)

48
Q

2nd most common relation of cementum to enamel:

A

butt joint (30%), 10% w space bw C and E

49
Q

Intermediate cementum is characterized by:

A

narrow zone of highly calcified amorphous tissue bw acellular cementum and dentin

50
Q

Where is intermediate cementum found?

A

cemento-dentinal unction of roots

51
Q

Is intermediate dentin a product of cementogenesis or dentinogenesis?

A

neither

52
Q

Enamel matrix protein found in intermediate cementum is likely a product of:

A

HRS

53
Q

Purported function of intermediate cementum:

A

reduce root sensitivity

54
Q

How many groups of EM cells are present in the bell Stag?

A

2

55
Q

Dental follicle cells lead to the formation of:

A

OEE cells, cementoblasts, PDL fibroblasts, Osteoblasts that form alveolar bone (check)

56
Q

Acellular cementum covers:

A

root surface

57
Q

These cells differentiate into cementoblasts:

A

dental follicle cells

58
Q

When does the differentiation of dental follicle cells to cementoblasts begin?

A

right after predentin formation

59
Q

TF? Cementum/ root dentin formation is coupled.

A

T

60
Q

Function of acellular cementum:

A

provides attachment for the tooth

61
Q

3 ways acellular cementum forms:

A

DF cells, pre-cementoblast differentiation, cementoblast differentiation on root (check)

62
Q

Location of dental follicle cells that can lead to the formation of acellular cementum (ACC):

A

parallel to HRS

63
Q

These cells can differentiate into pre-cementoblasts:

A

dental follicle cells

64
Q

When do dental follicle cells differentiate into pre-cementobalsts?

A

upon pre-dentin formation

65
Q

Is the migration of dental follicle cells to form predentin uni- or bi- directional?

A

uni

66
Q

When do pre-cementoblasts differentiate into cementoblasts and form acellular cementum on root dentin surface?

A

When they reach root dentin

67
Q

Cementum formation is couple with:

A

root dentin formation

68
Q

Shape of the pre-cementuoblasts that migrate to the predentin:

A

fibroblast like shape

69
Q

Shape of cementoblasts:

A

round (check)

70
Q

Function of cementoblasts:

A

active synthesis, secretion of cementum matrix component on root and mineralize

71
Q

3 major steps from dental follicle cells to dentin w embedded Sharpey’s fibers:

A

Differentiation, migration, secretion

72
Q

Function of acellular cementum:

A

connective attachemtn ofrmation during root formation

73
Q

What do cementoblasts secrete:

A

cementum ad collagen fibrils bw Sharpey’s fibers, non-collagenous matrix proteins that fill in space bw collagen fibers

74
Q

Function of Sharpey’s fibers:

A

attach to root dentin surface, anchor PDL collagen fibers to root surface

75
Q

What are Sharpey’s fibers?

A

Collagen fibers of PDL that are incorporated into cementum and alveolar bone

76
Q

What completes cementum formation & CT attachment ot root surface?

A

mineralization of cementum, collagen and Sharpey’s fibers

77
Q

in which directions do incremental lines run?

A

parallel to the interfaces of ACC and Root dentin as well as interface bw ACC and PDL collagen fibers

78
Q

Fate of HRS cells:

A

Epi rests

79
Q

ER are in what?

A

PDL

80
Q

What lines the interface bw the PDL and the ACC?

A

cementoblasts

81
Q

When does acellular cementum formation convert to cellular cementum formation?

A

When 2/3 of root formation is completed, after acellular cementum formation once the tooth is in occlusion

82
Q

What makes 2’ cementum?

A

cells entrapped in matrix they secrete (check?)

83
Q

Unique morphology of cellular cementum:

A

cementoytes within cementum: lacunae - cell body, canaliculi - cell processes

84
Q

What are th cell bodies of cementocytes?

A

lacuna

85
Q

What are the cell processes of cementocytes?

A

canaliculi

86
Q

Function of cellular cementum:

A

adaptive role in response to tooth wear and movement

87
Q

cellular cementum is assoc w:

A

repair and regeneration of periodontal tissue

88
Q

When are reversal lines created?

A

during reversal from resorptive to formative phase,, cementum can repair itself

89
Q

This repairs cementum:

A

cementum

90
Q

Age-related changes of cementum:

A

CC inc, thickening the ACC< the area covered by cellular cementum inc, surface becomes more irregular, only surface layer of cementocytes visible, other lacunae appear empty