Renal Flashcards
What is absorbed in the proximal convoluted tubule?
Glucose/amino acids/carboxylate/bicarbonate/phosphate/
65% sodium and potassium
50% urea
Calcium and phosphate
Where is ADH released from?
The posterior pituitary gland
Where does ADH act on in the kidney?
The collecting duct and distal convoluted tubule
Loop of henle
What is the action of ADH
Increases water re-absorption; increases aquaporins in the collecting duct and distal convoluted tubule, increased urea excretion in the collecting duct and increased sodium re-absorption in the loop of henlé
What is the function of the basement membrane?
Semi permeable membrane found in the glomerulus which prevents large components of blood like red blood cells and proteins from leaking through.
What is the total body volume?
42 litres (60% body weight)
What is the total blood volume?
5.6 litres
What are the routes of fluid loss?
lungs, urine, skin, faeces
What are the average fluid losses each day?
lungs - 400ml/day
skin- 1 litre/day
Urine -1.5 litres (minimum 400ml per day)
Faeces - 100ml/day
What is the maintenance fluid requirement?
30ml/kg/day
How much fluid in the body in extracellular?
14 litres
What is extracellular fluid made up of?
14 litres: Plasma (3.5 litres) and insterstitial fluid (10.5 litres)
What volume is intracellular fluid?
28 litres
What causes stimulates angiotensinogen production?
oestrogen and glucocorticoids
What is the function of angiotensin II?
Vasconstriction and stimulates aldosterone secretion
