Thyroid Gland Flashcards
1
Q
What is the Wolff Chaikoff Effect?
A
High levels of I- inhibits the organification and synthesis of thyroid hormones
2
Q
What are the actions of Perchlorate & Thicynate?
A
They are competitive inhibits of the Na+/I- cotransporter (inhibiting thyroid hormone synthesis; treatment for hyperthyroidism)
3
Q
What is the action of PTU?
A
It inhibits thyroid peroxidase (treatment for hyperthyroidism)
4
Q
What is Pendrin?
A
It transports Iodide into the blood; to make Iodine
