Hormones

Question 1

sub working viacGMP

Answer 1

ANF

NO

Question 2

is there req for 2 messenger for rec with intrinsic protein kinase activity

Answer 2

no

eg:insulin

Question 3

camp and cgmp are degraded by

Answer 3

phosphodiestrases

Question 4

soluble guanylate is activated by

Answer 4

NO

Question 5

name substances acting via guanylate receptors

Answer 5

ANF: vasodilation ; na and water excn

E.coli stable toxin: inc CFTR and diarrhoea

Question 6

cGMP requires______ G protein

Answer 6

no

also insulin

Question 7

types of G proteins

Answer 7

1.trimeric
Gi
Gs
Gq
Gt(transducin)
2.monomeric
p21ras G protein

Question 8

ADP ribosylation of G proteins is caused by which bacteria

Answer 8

cholera Gs
e.coli Gs
pertussis toxin Gi

Question 9

receptor having tyrosine kinase activity

Answer 9

insulin

growth factor receptor

Question 10

structure of rhodopsin

Answer 10

7 pass

Question 11

uniqness of rods and cones

Answer 11

membrane is partiallt depolarised in dark so nt glutamate is continuosly released
stimulates release of gaba from bipolar
inhibits optic nerve
in light, dec in cGMP level due to +PD which leads to closing of Na chanels and repolaeisation