Exam 4- Chronic Kidney Disease Complications

Question 1

Name the 5 major Complications of CKD discussed in class. (think My Aunt Flow has CKD Complications)

Answer 1

M-Metabolic acidosis/ mineral + bone disorders
A- Anemia
F-Fluid/electrolyte disorder
C- CVD

Question 2

What 3 factors directly stimulate PTH?

Answer 2

• decrease calcium levels
• decreased calcitriol levels (active vitamin D)
• phosphate retention

Question 3

What is used to treat MBD secondary to CKD? (3)

Answer 3

• phosphate binders
• Calciumimetics
• Vitamin D

Question 4

What is the MOA of phosphate binders?

Answer 4

They bind phosphate (food) in the GI to form aluminum, calcium, magnesium phosphate which is excreted via feces.

Question 5

Phosphate binding

-Stage 3, 4, 5 CKD (1st line)

Answer 5

Ca based phosphate binders are 1st line: with increase in phosphate or decrease in Ca as well as increase in phosphate and increase or in range Ca level.

Question 6

Phosphate binding

-Stage 5 CKD- dialysis

Answer 6

Non-calcium based phosphate are used (only FDA)

Question 7

What is the maximum amt of Ca should be taken?

Answer 7

2000 mg