Microbiota

Question 1

What are 4 things the microbiota has to offer?

things discovered from gnotobiotic mice and the knocking out of germs

Answer 1

1. Improves gut motility (increases muscle development via signaling with secondary bile acids)
2. Stimulates GALT proliferations
3. Increases epithelium turnover/ Increases lamina propria cellularity
   - appear to increase functionality for absorbing nutrients.
4. Production of short chain fatty acids in the colon.
   - Germ free mice have less body fat and epididymal fat rendering them less fertile.
5. Supply essential amino acids/supply vitamins (K, B12, folic acid, biotin, pantothenate)
6. Bile acid recycling
7. innate defense system: toxin degradation, produce antimicrobial factors, compete with pathogens for nutrients.
8. But also help viruses. And inhibiting them may help prevent viral infections.