Succinylcholine

Question 1

Brand name of Succinylcholine

Answer 1

Anectine

Question 2

Drug class of Succinylcholine

Answer 2

Neuromuscular blocker, depolarizing; skeletal muscle relaxant

Question 3

Indications of Succ.

Answer 3

Rapid Sequence Intubation (RSI)

Question 4

Mechanism of Action of Succ.

Answer 4

Ultra-short-acting depolarizing skeletal muscle relaxant that mimics acetylcholine as it binds with the cholinergic receptors on the motor end plate, producing a phase 1 block as manifested by fasciculations.

Question 5

Contraindications of Succ.

Answer 5

Acute narrow-angle glaucoma, penetrating eye injuries, malignant hyperthermia. Acute injury after multisystem trauma, major burns, or extensive muscle injury. Inability to control airway or support ventilation with oxygen and positive pressure.

Question 6

Adverse effects of Succ.

Answer 6

Apnea, respiratory depression, bradydysrhythmia, tachydysrhythmia, dysrhythmia, cardiac arrest, salivation, prolonged muscle rigidity, rhabdomyolysis, malignant hyperthermia, increased intraocular pressure, hyperkalemia (trauma patients)

Question 7

Precautions of Succ.

Answer 7

Oxytocin, Beta Blockers and Organophosphates

May potentiate effects, diazepam can reduce duration of action

Question 8

Adult and pediatric dose and admin of Succ.

Answer 8

Adult: 1 to 1.5 mg/kg rapid IV. Repeat once if needed.
Pedi: 1 to 1.5 mg/kg rapid IV/IO
Onset of 1 minute, Peak 1 to 3 minutes, Duration 5 to 10 minute