Meiosis Flashcards

1
Q

What is the goal of meiosis?

A

To make genetically diverse gametes-1 copy of each chromosomes-leads to a possible of 4 gametes

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2
Q

______ are separated in Meiosis 1

A

homologous chromosomes

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3
Q

______ are separated in Meiosis 2

A

sister chromatids

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4
Q

Overview of meiosis in 3 sentences

A
  • two rounds of meiosis
  • chromosomes duplicate once
  • nuclei divide twice
  • homologous chromosomes pair up
  • homologies undergo crossing over
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5
Q

Prophase 1

A

homologous chromosomes pair and are held together by synaptonemal complex
crossing-over (recombination) occurs during prophase 1

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6
Q

Metaphase 1

A

Centromeres do not divide and sister chromatids are not separated, but chromosomes are still pulled to opposite ends

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7
Q

Telophase 1

A

only 1 homologous chromosome in each cell after meiosis

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8
Q

Meiosis 2

A

Separation of sister chromatids

this is where the gametes are made and are genetically different than parents

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9
Q

Haploid cells carry….

A

half of the genetic information

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10
Q

Meiosis leads to….

A

4 haploid cells that are not genetically the same

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11
Q

How does Meiosis 1 ensure genetic diversity?

A

Independent assortment of homologous chromosomes

Recombination

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12
Q

Law of Segregation

A

Movement of homologous chromosomes to opposite poles at anaphase 1 of meiosis

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13
Q

Law of Independent Assortment

A

Independent alignment of different homologous pairs on the metaphase 1 spindle

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14
Q

Compare and contrast mitosis and meiosis

A

Mitosis-
homologous chromosomes do not pair do not exchange genetic material (very rare).
Occurs in somatic cellls
Haploid and diploid cells can undergo mitosis
One round of division
Mitosis is preceded by S phase (chromosome duplication)
sister chromatids attach to spindle fibers from opposite poles during metphase
the centromete splits at the beginning of anaphase
At the end of mitosis you get 2 identical cells that are both diploid

Meiosis-
Get 2 phases of division
Occurs in germ cells as part of the sexual cycle
Only diploid cells undergo meiosis
chromosomes duplicate prior to meiosis 1 but not before meiosis 2
Crossing over occurs between homologous chromosomes during prophase of meiosis
Homologous chromosomes (NOT SISTER CHROMATIDS) attach to spindle fibers from opposite poles
the centromere does not split during meiosis 1
sister chromatids attach to spindle fibers during metaphase 1
the centromere splits at the beginning of anapahse 2
At the end you have genetically diverse haploid cells that become gametes

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15
Q

Germ line

A

specialized germ cells set aside during embryogenesis

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16
Q

Gametogenesis

A

the formation of gametes

17
Q

In humans, oogenesis produces….

A

one ovum from each primary oocyte

18
Q

In humans, spermatogenesis produces…

A

four sperm from each primary spermatocyte

19
Q

Egg formation

A

asymmetrical meiosis, long meiotic arrest because meiosis 2 doesn’t start until puberty, may contribute to chromosome segregation errors

20
Q

asymmetrical v symmetrical meiosis

A

you know this

21
Q

Sperm formation

A

symmetrical meiosis

mitosis and meiosis occur throughout lifetime

22
Q

fertilization

A

equals zygote formation, the sperm are introduced to the egg and insert its nuclei

23
Q

Non-disjunction

A

mistakes in chromosome segregation during meiosis 1 or 2

24
Q

Non-disjunction may result in inviable…

A

gametes or embryos

25
Q

Non-disjunction can also result in abnormal characteristics like

A

trisomy 21 down syndrome

26
Q

Aneuploids

A

an abnormal number of chromosomes in the cell