Neuroplasticity

Question 1

Mechanisms of neuroplasticity

Answer 1

Habituation
Learning
Synaptogenesis
Change in Cortical Maps
Recovery

Question 2

Decrease response to repeated benign stimuli

Answer 2

Habituation

Question 3

Describe long term potentiation

Answer 3

Glutamate NMDA is stimulated->
AMPA receptors bind to membrane->
Repeated binding=spine development->
Change of shape and branching of spine->
Inrease in gene expression

Question 4

What does long term depression do to synaptic connectivity

Answer 4

Decrease

Question 5

3 peripheral CT covers

Answer 5

Epneurium
Perineurium
Endoneurium

Question 6

PNS Injuries

Answer 6

Neurapraxia
Axonotmesis
Neurotmesis

Question 7

Demyelination with temporary conduction block

Answer 7

Neuropraxia

Question 8

Axon damage w/ endoneural tube intact

Answer 8

Axonotmesis

Question 9

Endoneural and perineurium disrupted

Answer 9

Neurotmesis

Question 10

Axonal sprouting is how neuron

Answer 10

Regenerates

Question 11

Entangled nerve sprout and schwann cells

Answer 11

Neuroma

Question 12

Regeneration happens w/in

How much growth per month?

Answer 12

3-4 days

1 inch

Question 13

What do schwann cells release for sprouting?

Answer 13

Neuronal Growth Factor

Question 14

2 types of sprouting?

Answer 14

Collateral and regenerative

Question 15

Injury of 2 or more nerves?

Answer 15

Multiple mononeuropathy

Question 16

Examples of multiple mononeuropathy?

Answer 16

DM
Vasculitis
Infection
Bacterial infection

Question 17

Increase in blood sugar?

Answer 17

DM

Question 18

Inflamed blood vessel?

Answer 18

Vasculitis

Question 19

HIV/lymes disease is an example of

Answer 19

Infection

Question 20

Leprosy is an example of

Answer 20

Bacterial infection

Question 21

Symmetrical lostt of sensory, motor, and ANS fibers

Answer 21

Polyneuropathy

Question 22

Polyneuropathy occurs

Answer 22

Distal->proximal

Question 23

Causes of Polyneuropathy?

Answer 23

Toxins
Metabolic disease
Autoimmune disease
Genetics

Question 24

CNS injuries

Answer 24

Laceration
Impact
Pressure
Circulatory
Poison
Degeneration
Genetic Programming
Excitotoxicity

Question 25

Post synaptic neuron dies from excess glutamate

Answer 25

Excitotoxicity

Question 26

Point of impact?

Rebound>?

Answer 26

Coup

Contre coup

Question 27

CNS synaptic changes after injury

Answer 27

• NT production and transport change effectiveness
• Denervation hypersensitivity
• Synaptic Hypereffectiveness
• Distribution of silent synapse

Question 28

Post synaptic neuron make more receptors b/c of damaged presynaptic neuron

Answer 28

Denervation hypersensitivity

Question 29

Presynaptic loss of branches that causes increase NT production

Answer 29

Synaptic hypereffectiveness

Question 30

Reorganize receptors on cell membrane

Answer 30

Disinhibition of silent synapse

Question 31

Recovery of CNS is ______

It engages mechanisms that _____

Answer 31

Limited.

Cause death to damaged neurons

Question 32

Types of recovery for CNS

Answer 32

Dormant paths awaken
Remodeling
Corollary axons
New paths created
Other area assumes function

Question 33

CNS testing

Answer 33

CN test
Motor control
Cognition
Vision
Emotions
Balance

Question 34

Sensory homonculus disorganization

Answer 34

Dystonia

Question 35

Dentate gyrus making new cell

Answer 35

Neurogenesis

Question 36

Use of muscle electric signal to power prosthetic

Answer 36

Myoelectric prostetics

Question 37

Regeneration of neurons happens in

Answer 37

Hippocampus and striate

Question 38

What develop and guide axons where they need to go?

Answer 38

Neurotropic factors