Pediatric

Question 1

describe intrauterine

Answer 1

passive absorption
zero direct application
not a priority
little understanding

Question 2

describe neonate

Answer 2

passive/active
direct application
not a priority

Question 3

describe infant

Answer 3

active/passive absorption
direct application
one of the focus groups

Question 4

describe child

Answer 4

active reabsorption
direct application
product choice important

Question 5

describe adolescent

Answer 5

active absorption
close to adult conditions
unique due to growth transistion

Question 6

influences of variable ADME

Answer 6

continuous growth
different diet/grwoth/nutrient requirement
lack of expression
age, weight, size variable

Question 7

4 properties of dosage forms

Answer 7

convenience
choice
reasonable priced
stable

Question 8

what is bioequivalence

Answer 8

different brands have the same active ingredient, concentration, and dose therfore same biological activity

Question 9

bad things about sweeteners

Answer 9

calories load
tooth decay
diabetic children
incompatible

Question 10

problems with colorants and flavors

Answer 10

allergenic
incompatible
no medicinal value
try to limit

Question 11

what is ethanol used for

Answer 11

solvent

absorption enhancer

Question 12

problems with lactose

Answer 12

intolerance

diarrhea

Question 13

problem with benzalkoium

Answer 13

bronchoconstriction

Question 14

problems with parabens

Answer 14

hypersensitivity

Question 15

problems wiht benzyl alcohol

Answer 15

metabolic acidosis

neurotoxicity

Question 16

tween problems

Answer 16

liver/kidney failure

Question 17

tartazine problems

Answer 17

urticaria

bronchoconstriction

Question 18

problems wiht propylene glycol

Answer 18

seizure, hyperosmolality

contract derm

Question 19

alcohol content for over 12

Answer 19

under 10%

Question 20

alcohol content for 6-12 years

Answer 20

under 5%

Question 21

alcohol content for under 6

Answer 21

under 0.5%

Question 22

benefits of oral admin

Answer 22

preferred by children 
convenient 
noninvasive
low cost
appropriate for all ages

Question 23

who is chewable forms appropriate for

Answer 23

over 3

Question 24

who is solid forms appropriate for

Answer 24

over 6

Question 25

problems with liquid

Answer 25

instbale have to measure dose mix with food and drink

Question 26

disadvantages of parenteral

Answer 26

``` invasive high cost complications higher volume more pain so require multiple injections for large dose no pediatric products ```

Question 27

disadvantages of pulmonary admin

Answer 27

higher cost | inappropriate for young children

Question 28

advantages of pulmonary

Answer 28

effective local action convenient non invasive higher cost

Question 29

what are inhalation devices for under 3 like

Answer 29

solution hospital use only need mask/device

Question 30

disadvantages of rectal admin

Answer 30

variable absorption unconventional inconvenient

Question 31

packaging of childrens products

Answer 31

distinctly different from adults useful drug info appealing to users provide dosing device