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Infectious > Schistosomiasis > Flashcards

Schistosomiasis Flashcards

1
Q

What is the infective stage for humans in schistosomiasis? (Harrison pp 1423)

A

Cercariae (Blood Flukes)

Metacercariae (Biliary Flukes)

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2
Q

What compromise the blood flukes? (Harrison pp 1423)

A

Schistosoma mansoni, japonicum, intercalatum, mekongi, haemotobium

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3
Q

True or false, all trematodes are hermaphroditic except schistosoma. (Harrison pp 1423)

A

True

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4
Q

What are the examples of Biliary Flukes? (Harrison pp 1423)

A

Clonorchis senesis, Opistorchis viverrrini, Opistorchis felienus, Fasciola hepatica, Fasciola gigantica

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5
Q

What compromise the Intestinal Flukes? (Harrison pp 1423)

A

Fasciolopsis buski and Heterophyes herterophyes

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6
Q

It is a lung fluke that may be seen in crayfish or crabs and globally known except in North America and Europe. (Harrison pp 1423)

A

Paragonimus westermani

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7
Q

It is a blood flukes that is seen in the China, Philippines and Indonesia. (Harrison pp 1423)

A

Schistomiasis japonicum

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8
Q

It is a blood flukes that is seen in Southeast Asia. (Harrison pp 1423)

A

Schistomiasis mekongi

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9
Q

It is a Intestinal flukes that is seen with ingestion of a freshwater or brackish-water. (Harrison pp 1423)

A

Heterophyes heterophyes

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10
Q

It is a useful indicator of infection and has significance in protective and immunopathologic. (Harrison pp 1423)

A

Peripheral blood eosinophilia

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11
Q

It is the main adaptive mechanism of survival of schistosomiasis in human. (Harrison pp 1424)

A

Trilaminar to Heptalaminar

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12
Q

Sexually mature worms like S. mansoni, S. japonicum, S. mekongi and S. intercalatum goes to which part of the body and also where they deposit their ova? (Harrison pp 1424)

A

Intestinal veins

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13
Q

Sexually mature S. Haematobium goest to which part of the body and also where they deposit their ova? (Harrison pp 1424)

A

Pelvic Veins

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14
Q

True or False: All forms of Schistosoma infection are associated with subclinical systemic morbidities that cause significantly affect the physical and cognitive performance like growth stunting, undernutrition and aniemia. (Harrison pp 1425)

A

True

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15
Q

What are initially recruited in granuloma (Schistosomula) formation? (Harrison pp 1425)

A

Phagocytes
Antigen specific T cells
Eosinophils

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16
Q

What is recruited later in granuloma formation? (Harrison pp 1425)

A

Fibroblasts
Giant cells
B lymphocytes

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17
Q

Where does granuloma formation occurs? (Harrison pp 1426)

A

Perisinusoidal sites

18
Q

What happened if there is perisinusoidal portal blockage? (Harrison pp 1426)

A

Portal hypertension
Portosystematic collaterals at the esophageal junction
Esophageal varices

19
Q

It is characteristically as fibrosis at periportal but may be diffuse. (Harrison pp 1426)

A

Symmer’s clay pipe-stem fibrosis

20
Q

In Schistosomiasis haemotobium, the granuloma formation occurs in the lower end of the ureters that obstructs the urinary flow, which eventually leads to the following: (Harrison pp 1426)

A

Hydroureter

Hydronephrosis

21
Q

Secondary infertility or subfecundity may result that involves what areas of the of female’s genitals? (Harrison pp 1426)

A

FUO
Fallopian tubes
Uterus
Ovaries

22
Q

It is during the phase of cercarial invasion, a form of dermitis that usually involved the S. mansoni and S. japonicum. (Harrison pp 1426)

A

Swimmer’s Itch

23
Q

It is a serum like sickness like illness with fever, generalized lymphadenopathy and hepatosplenomegaly. (Harrison pp 1426)

A

Katayama Syndrome

24
Q

What is the main clinical manifestations of chronic shistosomiasis? (Harrison pp 1426)

A

Species dependent

25
Q

It is the 1st clinical manifestation of hepatosplenic phase. (Harrison pp 1427)

A

Bleeding from esophageal varices

26
Q

It is considered as human carcinogen. (Harrison pp 1427-1428)

A

Schistosoma haemotobium
Clonorchis sinensis
O. viverrini

27
Q

Pulmonary schistosomiasis produces what disease? (Harrison pp 1427)

A

Acute necrotizing arteriolitis

Granuloma formation

28
Q

What are the most common symptoms of pulmonary schistomiasis? (Harrison pp 1427)

A

Cough, fever and dyspnea

29
Q

It is the 2nd most common cause of epilepsy in endemic area and caused by S. japonicum. (Harrison pp 1427)

A

Jacksonian epilepsy

30
Q

It is associated with transverse myelitis. (Harrison pp 1427)

A

S. mansoni

S. haematobium

31
Q

It is the considered as screening test for Schistosomiasis. (Harrison pp 1427)

A

FAST-ELISA

32
Q

It is considered as confirmatory test for Schistosomiasis (Harrison pp 1427)

A

EITB (Enzyme-linked immunosorbent assay)

33
Q

If suspected to have Schistosomiasis, what is would request for diagnostic? (Harrison pp 1427)

A

Kato Thick Smear

34
Q

What is the treatment of choice for Schistosomiasis? (Harrison pp 1428)

A

Praziquantrel

35
Q

What is the adult dose and duration to be given for S. japonicum and mekongi? (Harrison pp 1428)

A

Praziquantrel 20mg/kg, 3 doses in 1 day

36
Q

What is the treatment of choice for Fasciola hepatica and Fasciola gigantica? (Harrison pp 1428)

A

Triclabendazole 10mg/kg ONCE

37
Q

It is Chinese or oriental fluke and endemic among fish-eating mammals. (Harrison pp 1428)

A

Clonorchis sinensis

38
Q

It is found on zoonitic cats and dogs. (Harrison pp 1428)

A

Opistochorchis viverrini

Opistochorchis felineus

39
Q

Where do liver (Biliary) flukes matures? (Harrison pp 1428)

A

Bile cannaculi

40
Q

It is related with cholangiocarcinoma. (Harrison pp 1428)

A

C. sinensis (China)

O. viverrini (Thailand)

41
Q

It is endemic among sheep raising countries (Harrison pp 1428)

A

Fasciola hepatica

Fasciola gigantica

42
Q

It is observed among patient with brownish sputum or frank hemoptysis. (Harrison pp 1429)

A

Pulmonary paragonimiasis

Infectious (7 decks)

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