Chap-17 Porphyria Flashcards

1
Q

Mitochondrial disorder p.

A
  1. ALA-synthase
  2. Heridatary copro-P.
  3. Variegate P.
  4. Erythropoeitic Proto.P
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2
Q

Cytoplasmic disorder p.

A
  1. ALA dehydrates def P.
  2. A.I.P
  3. Cong. Erythropoeitci P.
  4. P.Cutanae tarda
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3
Q

ALA synthase:

A

Succinyl co-A + Glycine —> ALA

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4
Q

ALA-dehydratase

A

ALA–> PBG

ALA dehy-deff

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5
Q

PBG deaminase

A

PBG –> OH’methylbilane (HMB)

A.I.P

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6
Q

URO-Gen 3 synthase

A

Oh’Methylbilane(HMB) –> Urogen III

Cong erythropoeitic P.

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7
Q

URO-GenIII-decarboxylase

A

Urogen3–>Copro III

P.Cutanea tarda

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8
Q

COPRO.III-Oxid

A

CoproIII–> Protogen9

Heridatary copro.P

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9
Q

Protogen.oxid

A

Protogen9–> Proto 9

variegate.P

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10
Q

Ferrechelotase

A

Proto-9—>Heme

Erythropoeitic proto.P

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