6 - Cell division Flashcards
(53 cards)
Cell cycle stages (5)
M G0 G1 S G2
What happens in the M phase of the cell cycle? (3)
Cell growth stops
Mitosis (PMAT)
Cytokineses
What happens in the G0 phase of the cell cycle?
The cell may go through:
Apoptosis (programmed cell death)
Differentiation
Senescence (cell can only divide a certain n.o of times)
Some cells can be in the cycle indefinitely
What happens in the G1 phase of the cell cycle? (4)
Cell grows
TRANSCRIPTION of genes - make RNA
Protein synthesis
Organelles duplication
G1 CHECKPOINT (4)
CHECK FOR: cell size DNA damage growth factors nutrients
What happens in the S phase of the cell cycle? (4)
DNA replicates
|—-> therefore each chromosomes has a pair of identical sister chromatids.
Phase happens quickly
|—-> because the exposed DNA are exposed and are susceptible to mutagen agents.
What happens in the G2 phase of the cell cycle? 5
Cell grows
Protein microtubles reassemble into spindle fibres.
G2 CHECKPOINT (3)
CHECK FOR:
cell size
DNA replication
DNA damage
Stages of mitosis (4)
Prophase
Metaphase
Anaphase
Telophase
Interphase
During interphase:
DNA replicated and checked
Protein synthesis occurs in the cytoplasm
Mitochondria grow and divide
Prophase
prepare
Chromosomes copied to form 2 chromatids
Chromosome condense
Nuclear envelope breaks down
Centrioles move to opposite poles of the cell
Spindle fibres extend to the middle of the cell
Metaphase
middle
Chromosomes line up at the equator of the cell forms metaphase plate.
Spindle fibres attaches to the centromere of the chromosomes.
Anaphase
away
Spindle fibres contract - split the centromere - chromatids are separated - dragged to poles - centromere lead
Complete set of chromosomes at each pole
Telophase
two
Chromatids reach the poles and uncoil
Nuclear envelope reforms - forming 2 nuclei
Cytokinesis follows
Importance of mitosis (3)
Assexual reproduction
Growth of cells
Replication and repair of cells
Importance of Meiosis (1)
To produce sex cells (gametes)
Prophase I
Chromatin condense & chromosome supercoils
Nuclear envelope breaks down
Chromosomes are in HOMOLOGOUS pairs = Bivalents
Chromatids entangle = Crossing over
Metaphase I
Chromosomes attach at the equator of the spindle - joined at the centromere
The homologous pairs are arranges randomly = Independent assortment
Anaphase I
Members of each homologous chromosomes are pulled apart by motor proteins
The crossed-over areas separate at the chiasmata leading to an area of swapped alleles/chromosomes
Telophase I
Two new nuclear envelope form and the cell divides via cytokinesis
Each new nucleus has half the number of chromosomes as the original but still has two chromatids.
Prophase II
The nuclear envelope breaks down
Chromosome coil and condense
The chromosomes are no longer identical due to the crossing over from P1 = Independent assortment
Spindle forms
Metaphase II
The chromosome attach to the spindle (by the centromere) and pilled to the metaphase plate
Chromatids are randomly arranged
Anaphase II
Centromeres divide
Chromatids are pulled apart by motor proteins - towards the poles
Chromatids are randomly segregated
Telophase II
Nuclear envelope form around 4 haploid cells