6 STIs: chlamydia Flashcards

(36 cards)

1
Q

what type of organisms are chlamydia?

A

obligate intracellular bacteria

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2
Q

what are the implications of chlamydia being an obligate intracellular bacteria?

A

they do not grow on routine laboratory media - has implications for diagnostic methods

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3
Q

what is the infective form of chlamydia?

A

the elementary body, which develops within the host cell into the reticulate body (having network of veins etc.)

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4
Q

what happens to the reticulate bodies of chlamydia which developed within host cells from elementary bodies?

A

reticulate body replicates eventually reverting back to elementary bodies, which leave the cell to infect other cells (process begins again)

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5
Q

how does chlamydia in females commonly present?

A

asymptomatic

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6
Q

where do the chlamydia organism in females infect and replicate?

A

infects and replicates within the epithelium of the cervix and urethra

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7
Q

what can ascending infections of chlamydia in females lead to?

A

if involves the upper genital tract, can result in clinical / subclinical pelvic inflammatory disease (PID)

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8
Q

how do PID from ascending infections of chlamydia involving upper genital tract present?

A

as endometritis / salpingitis

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9
Q

what is a rare complication of PID from ascending chlamydia infection resulting in PID?

A

perihepatitis

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10
Q

what is perihepatitis?

A

inflammation of the serous or peritoneal coating of the liver

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11
Q

how do most cervical infections present?

A

asymptomatic

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12
Q

what is cervical infection an important cause of?

A

mucopurulent cervicitis

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13
Q

what can urethral infection lead to?

A

‘acute urethral’ syndrome = a sequel of urethral infection

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14
Q

how does urethral infection present?

A

dysuria (pain) and frequency

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15
Q

which age group do urethral infections most commonly present in?

A

young sexually active women

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16
Q

what is the most important cause of pelvic inflammatory disease (PID) in the western world?

A

chlamydia trachomatis

17
Q

what is the major complication of pelvic inflammatory disease (PID)?

A

tubal damage leading to infertility and ectopic pregnancy

18
Q

what is a well-established cause of perihepatitis?

A

neisseria gonorrhoea

Chlamydia trachomatis also has a role to play

19
Q

how does chlamydia infection in men usually present?

A

as urethritis

20
Q

what is Reiters syndrome?

A

urethritis, conjunctivitis and arthritis are the classical triad manifestations associated with this syndrome

21
Q

which gender is Reiters syndrome predominantly in?

A

male patients

22
Q

what is Reiters syndrome a complication of?

A

acute epididymitis

23
Q

what can Chlamydia trachomatis commonly cause in sexually active individuals?

A

ocular infections

eye infections

24
Q

what is a source of Chlamydia trachomatis in neonate?

A

cervical infection in pregnant women

25
what is the most common infection in neonates?
conjunctivitis
26
what does untreated conjunctivitis from Chlamydia trachomatis in neonates lead to?
neonatal pneumonia
27
what is important about specimen collection of Chlamydia?
quality of specimen | as Chlamydia trachomatis is an intra cellular pathogen, it is essential that cell are present in the sample
28
how do you collect a specimen of Chlamydia trachomatis in males?
urethral swab OR first catch urine
29
how do you collect a specimen of Chlamydia trachomatis in females?
endocervical swab | urine
30
what is important when collecting an endocervical swab for Chlamydia trachomatis in females?
any pus is first removed from the cervix, and that good quality cellular material is obtained
31
when can urine be used in collecting a specimen of Chlamydia trachomatis in females?
may be used for molecular methods, but less sensitive than an endocervical swab
32
what is the potential value of using urine specimens in collecting a specimen of Chlamydia trachomatis in females?
for population screening, patients may provide their own specimens whereas an endocervical swab is time consuming
33
what are the cons of using endocervical swab in collecting a specimen of Chlamydia trachomatis in females?
requires a trained member of staff to take the specimen | less acceptable to the patient
34
what do you test for to check Chlamydia trachomatis in neonates?
eye swab | pneumonia
35
how do you carry out an eye swab to collect a sample of Chlamydia trachomatis in neonates?
remove any pus | invert eyelid and scrape conjunctiva surface to obtain cellular material
36
how do you test for pneumonia in neonates?
serology is useful | differential on WCC (white cell count) may show eosinophilia