Blood products

Question 1

What does group A Rh- blood mean?

Answer 1

A-antigens on red cell membranes
Anti-B antibodies in plasma
Doesn’t have rhesus D antigen

Question 2

What does group AB Rh+ blood mean?

Answer 2

A and B antigens on red cell membranes
No antibodies in plasma
Has rhesus D antigen

Question 3

What blood can be given to anyone?

Answer 3

O Rh-

Question 4

What does group O blood mean?

Answer 4

No antigens on red cell membranes

Anti-A and Anti-B antibodies in plasma

Question 5

What blood products are there?

Answer 5

Whole blood
Platelets
Granulocytes
Fresh frozen plasma
Cryoprecipitate

Question 6

What cryoprecipitate used for?

Answer 6

Source of fibrinogen
Factor VIII
vWF

Question 7

What happens to blood to give someone red cells

Answer 7

Filtered
Anticoagulant added
Re-suspended in SAG-M
Stored at 2-6º
35 day shelf life

Question 8

What happens to make a platelet sample?

Answer 8

Pooled from 4 donors or done by apheresis from single donor
Stored at room temperature
Constantly agitated

Question 9

Where does fresh frozen plasma come from?

Answer 9

• From men to avoid risk of transfusion reaction risk
• Plasma from countries with low CJD risk for recipients born after 1996
• Frozen at -25º and stored for 36 months
• Used for clotting deficiencies

Question 10

What can cause haemolysis when giving blood products?

Answer 10

Wrong A or B antigen
Rapid intravascular haemolysis
Inflammatory cytokines
Circulatory collapse and renal failure
Need ITU