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KCSU17 Patho/Pharm Submodule 2 > Cardio Pharm- HTN > Flashcards

Cardio Pharm- HTN Flashcards

1
Q

Major options for HTN treatment

A

ACE inhibitors/ARBs
Thiazide diuretics
calcium channel blockers
beta blockers

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2
Q

which medications are best for young, white patient

A

ACE inhibitor and Beta Blockers

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3
Q

which medications are best for older patients, or black patients

A

thiazide diuretic and calcium channel blockers

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4
Q

ACE inhibitors

first line of agents

A 
heart failure 
pts with ST elevation MI
diabetes
systolic dysfunciton 
patient with CKD
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5
Q

ACE inhibitors MOA

A

comp. inhibitor of angiotensin converting enzyme in lung

prevents conversion of Angiotensin I and Angiotensin II

potent vasoCONSTRICTOR

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6
Q

ACE inhibitors SE

A

cough

angioedema

hypotension

hyperkalemia

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7
Q

ACE Inhibitor CIs

A

patient with prior history of angioedema

concomitant use with aliskirin (Rasilez)

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8
Q

drug example of ACE inhibitor

A

Lisinopril (Zestril)

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9
Q

ARBs indications

A

similar indications as ACE inhibitors

but it is used for those who don’t tolerate ACE inhibitors

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10
Q

ARBs MOA

A

blocks vasoconstrictor and aldosterone secreting effects of angiotensin II

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11
Q

side effects of ARBs

A

hypotension

hyperkalemia

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12
Q

ARB CI

A

concomitant use with aliskirin (Rasilez)

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13
Q

ARB example drug

A

Iosartan (Cozaar)

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14
Q

Thiazide Diuretics

indications

A

HTN in black, elderly patient

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15
Q

Thiazide diuretics MOA

A

inhibits Na reabsorption in distal tubules

increases excretion of sodium and water as well as potassium and hydrogen ions

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16
Q

Thiazide diuretics SE

A

hypokalemia

17
Q

thiazide diuretics CI

A

sulfa drugs, anuria

18
Q

thiazide diuretics drug example

A

hydrochlorothiazide

19
Q

calcium channel blocker

indications

A

no absolute indications

dihydropyridine MC

20
Q

calcium channel blocker ex.

A

Amilodipine (Norvasc)

21
Q

calcium channel blocker

MOA

A

directly acts on vascular smooth muscle to produce peripheral arterial vasodilation reducing peripheral vascular resistance and BP

22
Q

calcium channel blocker

SE

A

peripheral edema

pulmonary edema

23
Q

calcium channel blocker CI

A

MI/angina
hypotension
peripheral edema

24
Q

beta blocker MOA

A

inhibitor of beta adrenergic receptors

25
Q

beta blocker SE

A

hypotension
bradycardia
AV block

26
Q

CI beta blocker

A

hypotension, 2 or 3 AV block, cariogenic shock, heart failure

KCSU17 Patho/Pharm Submodule 2 (14 decks)

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