Nephrology Flashcards

1
Q

A patient with stage 5 CKD presents to the ED with signs of uremia. You learn that the patient missed three dialysis appointments last week. ABG shows an uncompensated acid/base derangement. You expect that the pH will be ______ (high/low/normal) and the HCO3 will be ______ (high/low/normal).

A

low, low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

A patient presents with a partially compensated metabolic acidosis. You expect that the patient’s minute ventilation will be ______ (increased/decreased).

A

Increased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

A diabetic patient presents with a decreased GFR and proteinuria. In addition to treatments for diabetes, which class of medication is most appropriate for this patient?

A

ACE-I/ARB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

You are treating a patient with AKI. Upon reviewing the patient’s labs, you find that the BUN:creatinine ratio is increased and the FENa is 0.9%. This patient’s AKI is most likely due to a ______ (prerenal/renal/postrenal) cause.

A

Prerenal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

You are treating a patient in the ICU for septic shock. The patient develops prerenal AKI. This progression is ______ (common/uncommon). What treatment is likely to be of greatest benefit for this patient?

A

Common, IV fluids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

A 38 year-old patient with a history of HTN refractory to aggressive medical therapy presents with bilateral flank pain. On exam, the kidneys are easily palpable. Labs show a decreased GFR. What is the most appropriate study to evaluate this patient?

A

Renal ultrasound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Among patients with CKD of all stages, the greatest cause of mortality is ______ ______.

A

Cardiovascular disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A patient is given a saline infusion that causes a dramatic shift of fluid into the intravascular space. The concentration of the saline was probably ______ (0.45%, 0.9%, 3%). This fluid is best described as ______ (hypotonic/isotonic/hypertonic).

A

3%, hypertonic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

An 8 year-old patient presents with hypertension, edema, and hematuria. UA is positive for protein, and the patient is hypoalbuminemic. Kidney biopsy is unremarkable. What is the most likely diagnosis?

A

Minimal change disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

An 8 year-old patient presents with hypertension, edema, and hematuria. UA is positive for protein, and the patient is hypoalbuminemic. Kidney biopsy is unremarkable. Which medication is most likely to be of benefit for this patient?

A

Prednisone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

An 8 year-old patient presents with hypertension, edema, and hematuria. UA is positive for protein, and the patient is hypoalbuminemic. Kidney biopsy is unremarkable. You ______ (warn/reassure) the patient’s parents since most children ______ (do/do not) recover completely from this disorder.

A

Reassure, do

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A patient presents with hemoptysis and acute renal failure. There is mild proteinuria and the UA is positive for dysmorphic RBCs, WBCs, and granular casts. Renal biopsy shows a linear deposition of anti-GBM antibodies. What is the most likely diagnosis?

A

Goodpasture’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

A patient presents with hemoptysis and acute renal failure. There is mild proteinuria and the UA is positive for dysmorphic RBCs, WBCs, and granular casts. Renal biopsy shows a linear deposition of anti-GBM antibodies. What are the three components of treatment for this patient?

A

Plasmapheresis
Prednisone
Cyclophosphamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q
Which of the following IV fluids is least appropriate for intravascular volume replacement in a dehydrated patient?
A. D5W
B. Normal saline
C. Lactated ringers
D. 5% Albumin
A

A. D5W

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

A patient with a history of chronic renal failure on dialysis presents with lethargy and confusion. You review the patient’s EKG and notice tall, peaked t-waves. Which disorder do you suspect?

A

Hyperkalemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

A patient with a history of chronic renal failure on dialysis presents with lethargy and confusion. You review the patient’s EKG and notice tall, peaked t-waves. What is the most dangerous complication associated with this presentation?

A

Cardiac arrhythmia

17
Q

A patient with a history of chronic renal failure on dialysis presents with lethargy and confusion. You review the patient’s EKG and notice tall, peaked t-waves. Name three treatments that should be considered immediately.

A

Calcium
Insulin/dextrose
Sodium bicarbonate

18
Q

Severe, life-threatening neurological complications are most often associated with over-zealous correction of which electrolyte disorder?

A

Hyponatremia

19
Q

A patient presents with confusion, delirium, and weakness. Serum sodium is 115 and serum osmolarity is 275. Urine sodium level is 24. What is the most likely diagnosis?

A

SIADH

20
Q

A patient presents with polyuria, polydipsia, and nocturia. After 8 hours of water deprivation, the patient’s urine osmolality is 290. The patient is given a dose of DDAVP, and the urine osmolality increases to 500. What is the most likely diagnosis?

A

Central diabetes insipidus

21
Q

An otherwise healthy 35 year-old male presents with HTN that has been refractory to aggressive treatment. Oddly, the patient experienced a significant rise in serum creatinine after he was started on lisinopril. What is the best study to evaluate this patient’s condition?

A

Renal angiography

22
Q

In paramedic school, I got a 70 on my renal disorders exam. In undergrad A&P, I got a 60 on a renal anatomy test. Back in January, I got a 50 on the med phys exam for renal physiology. Last week, I got a 40 on the renal pathophysiology exam, and after tomorrow my GPA is going to require dialysis. What accounts for this progressive and apparently irreversible decline in renal function?

A

Chronic renal failure

23
Q

A patient with a history of chronic kidney disease presents with chest pain. On examination, you note a pericardial friction rub. Cardiac workup is otherwise unremarkable. The GFR is 10. What treatment is most likely to be of benefit to this patient?

A

Hemodialysis

24
Q

A patient presents with chronic kidney disease, HTN, and T2DM. It is most likely that the diabetes ______ (caused/was caused by) kidney disease, and that the HTN ______ (caused/was caused by) the kidney disease.

A

caused, was caused by

25
Q

A patient with a history of SLE presents with edema, HTN, HLD, proteinuria, and lipiduria. Renal biopsy shows diffuse, granular deposits along the GBM. Electron microscopy shows a “spike and dome” pattern. What is the most likely diagnosis?

A

Membranous glomerulonephritis

26
Q

A 30 year-old male patient presents 2 days post-URI with hematuria. Which glomerular disease is most likely to blame?

A

IGA nephropathy (Berger’s disease)