Pain managment Flashcards by Calum Macindoe | Brainscape

Q

Metastatic cancer with bone pain treatment;

A

Parecetamol

NSAID i.e diclofinac, (if not contraindicated)

Opiods i.e moprhine

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Q

What are some nsaids?

A

Diclofinac, naproxen, celecoxib

many side effects

lots of contrindications

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Q

What are some opiods?

A

morphine, oxycodone, methadone

increase release of GABA (mu receptors)

Minor side effects

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Q

What are analgesics with novel actions?

A

•Amitriptyline•Gabapentin•Ketamine

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Q

What is Amitriptyline action

A

Serotonin and noradrenaline reuptake inhibition

increases endogenous opiods

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Q

What is gabapentin?

A

gaba analogue, though no gaba effects

Decreases Ca inwards flux

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Q

What is pain?

A

Physical and psyhological sensation i.e psyche can make it worse

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Q

Where do nsaids act?

A

Cyclooygenase inhibition

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Q

how does morphine function?

A

Increased GDP

increased GABA release

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