Thrombocytopaenia Flashcards
1
Q
Define Thrombocytopaenia
A
- Platelets <150x10*9/l
2
Q
Failure of platelet production as cause
A
- Aplastic anaemia
- Drugs (tolbutamide, chlorothiazides)
- Viruses (EBV. CMV, Varicella)
- Bone marrow infiltration (leukaemia, lymphoma, carcinoma, myelofibrosis)
- Alcohol
3
Q
Shortened platelet survival as cause
A
- ITP
- DIC
- Drugs (heparin, quinine, bendroflumethiazide, methotrexate, phenytoin, ranitidine, NSAIDs)
- Alcohol
- Infection
- Secondary autoimmune (SLE, CLL, HIV)
