table 17-6 Flashcards

1
Q
Gastrointestinal Carcinoid Tumors: Esophagus  
Fraction of GI carcinoids
Mean patient age (yr)
Location
Size
Secretory product(s)
Symptoms
Behavior
Disease associations
A
1%
Rare
distal
Limited data (size)
Limited data (secretory products)
Dysphagia, weight loss, reflux
Limited data
None
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2
Q
Gastrointestinal Carcinoid Tumors: stomach
Fraction of GI carcinoids
Mean patient age (yr)
Location
Size
Secretory product(s)
Symptoms
Behavior
Disease associations
A
<10%
55
Body and fundus
1-2 cm, multiple; >2 cm, solitary
Histamine, somatostatin, serotonin
Gastritis, ulcer, incidental
Variable
Atrophic gastritis, MEN-I
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3
Q
Gastrointestinal Carcinoid Tumors: Proximal Duodenum
Fraction of GI carcinoids
Mean patient age (yr)
Location
Size
Secretory product(s)
Symptoms
Behavior
Disease associations
A
<10%
50
Proximal third, peri-ampullary
0.5-2 cm
Gastrin, somatostatin, cholecystokinin
Peptic ulcer, biliary obstruction, abdominal pain
Variable
Zollinger-Ellison syndrome, NF-1, sporadic
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4
Q
Gastrointestinal Carcinoid Tumors: Jejunum and Ileum
Fraction of GI carcinoids
Mean patient age (yr)
Location
Size
Secretory product(s)
Symptoms
Behavior
Disease associations
A
>40%
65
Throughout
<3.5 cm
Serotonin, substance P, polypeptide YY
Asymptomatic, obstruction, metastatic disease
Aggressive
None
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5
Q
Gastrointestinal Carcinoid Tumors: Appendix
Fraction of GI carcinoids
Mean patient age (yr)
Location
Size
Secretory product(s)
Symptoms
Behavior
Disease associations
A
<25%
All ages
Tip
0.2-1 cm
Serotonin, polypeptide YY
Asymptomatic, incidental
Benign
None
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6
Q
Gastrointestinal Carcinoid Tumors: Colorectum
Fraction of GI carcinoids
Mean patient age (yr)
Location
Size
Secretory product(s)
Symptoms
Behavior
Disease associations
A
<25%
60
Rectum > cecum
>5 cm (cecum); <1 cm (rectum)
Serotonin, polypeptide YY
Abdominal pain, weight loss, incidental
Variable
None
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