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PT3 ID 1 (HIV) > Antibiotic drugs, moa, coverage > Flashcards

Antibiotic drugs, moa, coverage Flashcards

1
Q

Penicillin G

A

IV (no e- withdrawing group)

streptococcus, NEVER staph

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2
Q

Penicillin v/k

A

oral

streptococcus, NEVER staph

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3
Q

Oxacillins

A

oral

staph only

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4
Q

nafcillin

A

staph only

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5
Q

ampicillin

A

gram+

susceptible to beta-lactamase

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6
Q

amoxicillin

A

gram+

susceptible to beta-lactamase

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7
Q

ticarcillin

A

gram-

pseudomonas

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8
Q

piperacillin

A

good gram -/+
pseudomonas
enterococci
anaerobes

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9
Q

imipenem/meropenem

A

some gram+
broad gram-
pseudomonas

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10
Q

ertapenem

A

some gram+
broad gram-
NO pseudomonas, enterococcus, acinetobacter

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11
Q

aztreonam

A

gram-
enterobacteriacea
pseudomonas

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12
Q

beta lactam drugs

A 
penicillins
penems
aztreonam
cephalosporins
clavams
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13
Q

1st gen cephalosporins

A

cephalexin
cefazolin
cefadroxil

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14
Q

1st gen cephalosporin coverage

A

broad gram+

no MRSA

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15
Q

2nd gen cephalosporins

A

cefuroxime
cefoxitin
cefproxil

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16
Q

2nd gen cephalosporin coverage

A

broad gram+

some e. coli and klebsiella

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17
Q

3rd gen cephalosporins

A 
ceftriaxone
cefixime
cefpodoxime
cefdinir
cefotaxime
ceftazidime
18
Q

3rd gen cephalosporin coverage

A

some gram+

good for gram- besides pseudomonas

19
Q

3rd gen cephalosporin with pseudomonas coverage

A

ceftazidime

20
Q

4th gen cephalosporin

A

cefepime

21
Q

4th gen cephalosporin coverage

A

some gram+
good gram- including pseudomonas
no anaerobes

22
Q

vancomycin

A

glycopeptide
great gram+
MRSA
C. diff

23
Q

quinolones

A

ciprofloxacin
levofloxacin
moxifloxacin

24
Q

quinnolones moa

A

dna gyrase inhibitor

25
Q

quinolone coverage

A

good gram-
cipro pseudomonas
moxi anaerobes
levo best gram+

26
Q

trimethoprim moa

A

inhibits tetrahydrofolic acid production

27
Q

sulfamethoxazole moa

A

inhibits dihydropteroic acid production

28
Q

tetracyclines moa

A

ribosome inhibitors at 30s

29
Q

tetracyclines coverage

A

good gm+
active against MRSA
tigecycline active against VRE/anaerobes

30
Q

macrolides

A

erythromycin
clarithromycin
azithromycin

31
Q

macrolides moa

A

ribosome inhibitors at 50s

32
Q

macrolides coverage

A

streptococcus
some gm-
atypicals

33
Q

side effect of erythromycin

A

GI cramping

34
Q

side effect of clarithromycin

A

metallic taste

35
Q

clindamycin moa

A

ribosome inhibitor at 50s

36
Q

clindamycin coverage

A

good gm+

anaerobes

37
Q

clindamycin adverse effect

A

c. diff infection

38
Q

linezolid moa

A

inhibits ribosome at 50s

39
Q

linezolid coverage

A

MRSA

VRE

40
Q

linezolid side effects

A 
bone marrow suppression
MAO inhibitor (possible serotonin syndrome)

PT3 ID 1 (HIV) (5 decks)

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