Exam Flashcards

1
Q

Management of basal cell papilloma/seborrhoeic keratosis

A

Cryotherapy

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2
Q

Why are keratoacanthomas often excised?

A

Difficulty to distinguish between a SCC

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3
Q

Difference between a papule and a nodule?

A

Papule is less than 0.5cm

both are solid raised lesions

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4
Q

Staph infection around/within a hair follicle

A

Furnuncle

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5
Q

Functions of skin:

a) Langerhans cells
b) Merkel cells

A

a) Antigen presenting cells of the skin

b) light touch mechanoreceptors

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6
Q

Four layers of epidermis from deep –> superficial

A

Basal
Prickle
Granular
Stratum corneum

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7
Q

Pearly lesion with a rolled edge and telangiectasia

A

Basal cell carcinoma

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8
Q

BCC treatment options? (4)

A

Excision
Moh’s micrographic surgery
Cryotherapy
Imiquimod

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9
Q

What pattern of sun exposure broadly predisposes to a) BCC b) SCC?

A

a) intense, intermittent e.g. severe episodes of sunburn

b) chronic sun exposure e.g. an outside occupation like a farmer

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10
Q

Squamous cell carcinoma in situ is also known as…

A

Bowen’s disease

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11
Q

SCC precursor lesions? (2)

A

Actinic keratoses

Bowen’s disease

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12
Q

Patch of malignant melanocytes proliferating radially along the dermo-epidermal junction

A

Lentigo maligna

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13
Q

Commonest melanoma type?

A

Superficial spreading

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14
Q

Melanoma subtypes:

a) invasive growth from outset
b) seen on sole/palm/subungual
c) radially prolferating along the DEJ
d) diffuse blue/black patch on lower back/buttocks of a child

A

a) nodular
b) acral
d) lentigo maligna
d) Mongolian blue spot (congenital)

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15
Q

ABCDE criteria for assessing melanoctyic lesions?

A
Asymmetry
Border (irregular)
Colour (heterogenous)
Diameter (>6mm)
Evolution over time
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16
Q

Blistering skin disease:

IgG deposition in a “chicken-wire” pattern around cells within the epidermis

A

Pemphigus

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17
Q

Blistering skin disease:

linear IgG deposition along the basement membrane

A

Pemphigoid

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18
Q

Blistering skin disease:

IgA deposition in clusters around the dermal papillae

A

Dermatitis herpetiformis

19
Q

Mutations in which gene predispose to atopic eczema?

A

Filaggrin

20
Q

Management principles of eczema? (3)

A

Antimicrobial soap substitutes
Liberal use of emollients
Topical steroids

21
Q

Episodic eczema of the palms/soles, with bullae formation

A

Acute pompholyx eczema

22
Q

Management of rosacea? (3)

A

Trigger avoidance
Topical metronidazole
Antibiotics/roaccutane

23
Q

What treatment should be avoided in rosacea and why?

A

Topical steroids- cause widespread facial erythema and rebound flares

24
Q

Management of acne? (4)

A

Benozyl peroxide
Antibiotics
Isotretinoin
COCP/Dianette

25
Q

Signs of chronic venous hypertension? (5)

A
Stasis eczema
Hyperpigmentation
Lipodermatosclerosis
Varicose veins
Atrophie blanche
26
Q

Painful, palpable purpuric lesion –> punched out ulcer?

A

Vasculitic ulcer

27
Q

Mainstay of venous ulcer treatment?

A

Compression bandaging

28
Q

Violaceous plaques –> atrophy to become brown/yellow, seen in diabetics

A

Necrobiosis lipoidica

29
Q

Treatment of impetigo?

A

Fusidic acid if localized, flucloxacillin if generalized

30
Q

Causative agent of cat-scratch disease?

A

Bartonella

31
Q

Treatment of localized fungal disease?

A

Terbinafine, miconazole, clotrimazole (antifungals)

32
Q

Risk of systemic antifungal treatment?

A

Hepatotoxicity

33
Q

Treatment of viral warts? (4)

A

Salicylic acid (“wart paint”) for 12 weeks
Cryotherapy
Podophyllotoxin
Imiquimod

34
Q

Fluid-filled blister on finger due to direct inoculation of herpes virus?

A

Herpetic whitlow

35
Q

Causative agent of molloscum contagiosum?

A

Pox virus

36
Q

Multiple purplish patches caused by herpes virus 8

A

Kaposi sarcoma

37
Q

Child with fever, severe sore throat and vesicular rash over pharynx? Causative agent?

A

herpangina from coxasckie virus

38
Q

HPV subtypes:

a) common warts
b) genital warts

A

a) 1, 2, 4

b) 6, 11, 16 and 18

39
Q

Sites favoured by psoriasis?

A

Extensor surfaces of knees and elbows

40
Q

Nail involvement in psoriasis? (3)

A

Pitting, oncholysis, subungual hyperkeratosis

41
Q

Management of psoriasis?

A
Vitamin D analogues
Steroids for flares
Narrowband UVB
Coal tar preparations
Dithranol
42
Q

Eruption of itchy reddish-purple papules on wrist, back and genitalia + lacy white streaks in oral mucosa

A

Lichen planus

43
Q

Short flu-like illness –> single/few oval patches –> sudden eruption all over body

A

Pityriasis rosea

44
Q

Patches of discolouration caused by Malassezia yeast

A

Pityriasis versicolor