Neuromuscular Junction Blocking Agents Flashcards
1
Q
What do neuromuscular junction blocking agents do?
A
- Paralytic
- Blocking communication and stopping movement.
- Does not cause CNS depression
2
Q
What do neuromuscular junction blocking agent not do?
A
Cause CNS depression
3
Q
What do non depolarizing neuromuscular junction blockers do?
A
Act as antagonists to acetylcholine (ACh) at the NMJ and prevent depolarization of muscle cells.
4
Q
What do depolarizing neuromuscular junction blockers do?
A
Act as an Ash agonist, causing stimulation of the muscle cell and preventing it from repolarizing.
5
Q
True or False:
The neuromuscular junctions blocking agent are hydrophobic and do cross the blood brain barrier.
A
False:
They are hydrophilic and DO NOT cross the blood brain barrier.
6
Q
What is the main action of NMJ blocking agents?
A
Cause prolonged muscle contractions then paralysis
