Silver-Russell Syndrome

Question 1

What type of disorder is Russell-Silver Syndrome?

Answer 1

Uniparental disomy 7q32, 11p15

Question 2

What are the clinical characteristics for RSS?

Answer 2

1. Short stature
2. Fifth Finger clinodactyl
3. Normal head circumference
4. Elfin facies (triangular facies characterized by broad forehead, narrow chin)
5. Limb length asymmetry, hemihypertrophy
6. Developmental delay