6.2 Flashcards
(163 cards)
what is a phenotype
the apperance of a living organism
what is a phenotype influenced by
both its genotype and its environment
What have mutations contributed to
the process of evolution
What is a mutation and what may it involve
it is a change to the genetic material, this may involve changes to the strucutre of DNA or changes to the number or gross strucutre of chromosomes
what may lead to genetic variation
sexual reproduction and mutations
what is a mutagen
a physical or chemical agent that can increase the rate of mutations
What are some examples of mutagens which are physical agents
x-rays, gamma rays, UV lights
What are some examples of mutagens which are chemical agents
benzopyrene (in tobacco smoke), mustard gas, nitrous acid, reactive oxygen species
What are some examples of mutagens which are biological agents
some viruses, transposons (jumping genes, reminents of viral nucelic acid that’s become part of our genome), food contaminants like alcohol or mycotoxins from fungi
What may mutations be
harmful, advantageous or neutral
What are mutations that occur during gamete formation
persistent:they can be transmmitted through many generations without change and random:they are not directed by a need on the part of the organism in which they occur
when do chromosome mutations occur
during meiosis
what are the different types of chromosome mutations
deletion, inversion, translocation, duplication, non-disjunction, aneuploidy, polyploidy
What is deletion in chromosome mutations
part of a chromosome, containing genes and regulatory sequences is lost.
What is inversion in chromosome mutations
a section of a chromosome may break off, turn through 180degress then join again, although all genes still present, some may now be too far away from their regulatory nucelotide sequences to be properly expressed.
What is translocation in chromosome mutations
a piece of 1 chromosome breaks of and becomes attached to another chromosome, this may interfere with the regulation of the genes on the translocated chromosome.
What is duplication in chromosome mutations
a piece of a chromosome may be duplicated, overexpression of genes can be harmful, as too many of certain proteins or gene-regulating nucleic acids may disrupt metabolism
What is non-disjunction in chromosome mutations
1 pair of chromosmes or chromatids fails to separate, leaving 1 gamete with an extra chromosome. When fertilised by a normal haploid gamete, the resulting zygote has 1 extra chromosome. Down-syndrome is caused by non-disjunction.
What is aneuploidy in chromosome mutations
the chromosome number is not an exact multiple of the haploid number for that organism. Sometimes chromosomes or chromatids fail to separate during meiosis.
What is polyploidy in chromosome mutations
if a diploid gamete is fertilised by a haploid gamete, the resulting zygote will be triploid (have 3 sets of chromosomes). The fusion of 2 diploid gametes can make a tetraploid zygote. Many cultivated plants are polyploid (more than 2 sets of chromosomes)
what has genetic variation from sexual reproduction contributed to
evolution
Meiosis produces genetically different gametes, during meiosis what cause this genetic variation
allele suffling (swapping of alleles between non-sister chromatids) during crossing over in prophase 1), 9ndependant assortement of chromosomes in metaphase/anaphase 1 and independent assortment of chromatids in metaphase/anaphase 2
are gametes produced by meiosis individually and genetically similar
no, they are dissimilar
What are gemetes produced by meiosis
individually and geentically dissimilar, they’re haploid, containning 1 of each pair of homologous chromosomes and 1 allele for every gene