Chapter 6 and 7

Question 1

What is the most common form of hyperthyroidism?

Answer 1

Grave>s disease

Question 2

How do Ca+ molecules enter the cell?

3 ways

Answer 2

through voltage-gated calcium channels
or
ligand
or 
mechanically gated

Question 3

To what Ca can bind in the cell?

2

Answer 3

Calmodulin

Other Ca2+ binding proteins

Question 4

PLC converts membrane phospholipids into?

Answer 4

DAG + IP3

Question 5

What DAG does?

Answer 5

activates PK-C which phosphorylates proteins

Question 6

What IP3 does?

Answer 6

It causes the release of Ca2+ from organelles,
creating a Ca 2+ signal
slide 23

Question 7

The receptor-channel can be activated by 2 things:

Answer 7

GPCR or when a ligand binds to it

Question 8

What PK-C do?

Answer 8

it phosphorylates proteins

Question 9

What is the signal pathway for Na-K pump?

Answer 9

Receptor-channel

Question 10

GPCR binds to which nucleotide

Answer 10

guanosine

Question 11

What is the signal pathway for insulin?

Answer 11

tyrosine kinase

Question 12

The ___system is wired?

Answer 12

Nervous
its cell-to cell
slide 30

Question 13

Ant pit secretes

Answer 13

1- TSH
2-ACTH
3- GH
4- FSH
5-PRL
6- MSH

Question 14

Post pit secretes

Answer 14

ADH

Oxytocin

Question 15

2 anterior pituirary hormones that have and hypothalamic inhibiting hormone?

Answer 15

PRL : inhibited by PIH (dopamine)

GH, somatotropin : inhibited by SS aka GHIH

Question 16

Which hormone has a nonendocrine target ?

Answer 16

PRL

Question 17

describe synergism

Answer 17

1+1 >2

Question 18

describe permissiveness

Answer 18

2+0=0

Question 19

Peptide H are made as inactive :

Answer 19

Preprohormones and they are processed to prohormones in the ER.

Question 20

Endocrine cell secrete …

Answer 20

hormones

Question 21

Exocrine cell secrete …

Answer 21

products

Question 22

Iodine is essential for the production of…

Lack of iodine can cause … in adult

Answer 22

Thyroxine

goitre

Question 23

In children, when iodine is lacking or deficient, it can cause…

Answer 23

retard of growth and development

= cretinism

Question 24

TSH stimulates thyroid cells to produce…

Answer 24

T4 (thyroxine)
+
T3 (triiodothyronine)

Question 25

Adrenal cortex is stimulated by the hormone ___

and adrenal cortex secretes ____

Answer 25

ACTH (adrenocorticotropic hormone)

cortisol

Question 26

GH stimulates …

Answer 26

growth and metabolic effects

Question 27

Pineal gland produces…

Answer 27

Melatonin