Lymphoma

Question 1

Characteristics of Malignant Lymph nodes?

Answer 1

o	Hard
o	Painless
o	Firm
o	Fixed
o	Rubbery
o	Could be unilateral
o	Size of Malignant Lymph Node: No uniform size- but > 1.5 to 2 cm is an appropriate starting point for suspicion

Location: Palpable supraclavicular, iliac, or popliteal nodes of any size and epitrochlear nodes larger than 5 mm area these areas are most concern for malignant nodes

Increasing size and persistence over time are of greater concern for malignancy than a specific level of nodal enlargement

Question 2

Lymphadenopathy: Key risk factors

Answer 2

• Older age, firm, fixed nodal character, duration of greater than two weeks, and supraclavicular location
• In addition, a complete exposure history, review of associated symptoms, and a thorough regional examination help determine whether lymphadenopathy is of benign or malignant origin
  o ask about recent travel
• Unexplained lymphadenopathy without signs or symptoms of serious disease or malignancy can be observed for one month, after which specific testing or biopsy should be performed

Question 3

Lymphadenopathy in Viral Infection Clinical Features:

Answer 3

o	Enlarged lymph nodes
o	Bilateral
o	Mobile- not fixed like malignant nodes
o	Nontender/tender
o	Clearly demarcated
o	Size matters – usually less than 2 cm
o	Painful or tender lymphadenopathy